O04212
Gene name |
At2g40090 (T28M21.25) |
Protein name |
Putative ABC1 protein At2g40090 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G40090 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O04212
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O04212-F1 | Predicted | AlphaFoldDB |
20 variants for O04212
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_2_16740275_C_T | 10 | R>H | No | 1000Genomes | |
| tmp_2_16740260_A_G | 15 | V>A | No | 1000Genomes | |
| ENSVATH05688586 | 21 | C>S | No | 1000Genomes | |
| tmp_2_16740194_G_A | 37 | T>I | No | 1000Genomes | |
| ENSVATH13591839 | 72 | E>V | No | 1000Genomes | |
| ENSVATH13591838 | 94 | E>K | No | 1000Genomes | |
| ENSVATH05688569 | 135 | I>V | No | 1000Genomes | |
| ENSVATH13591829 | 192 | H>R | No | 1000Genomes | |
| ENSVATH05688550 | 291 | D>A | No | 1000Genomes | |
| tmp_2_16738571_T_A | 301 | Y>F | No | 1000Genomes | |
| ENSVATH05688544 | 368 | N>H | No | 1000Genomes | |
| tmp_2_16738181_T_C | 374 | K>R | No | 1000Genomes | |
| ENSVATH05688542 | 389 | E>A | No | 1000Genomes | |
| ENSVATH05688542 | 389 | E>V | No | 1000Genomes | |
| tmp_2_16738129_T_G | 391 | L>F | No | 1000Genomes | |
| tmp_2_16738000_C_A | 434 | Q>H | No | 1000Genomes | |
| ENSVATH05688535 | 470 | N>S | No | 1000Genomes | |
| ENSVATH00266896 | 511 | F>L | No | 1000Genomes | |
| tmp_2_16737738_C_G | 522 | V>L | No | 1000Genomes | |
| ENSVATH05688531 | 529 | I>V | No | 1000Genomes |
No associated diseases with O04212
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of mitochondrial membrane | The component of the mitochondrial membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| lipid homeostasis | Any process involved in the maintenance of an internal steady state of lipid within an organism or cell. |
| mitochondrion organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q06567 | MCP2 | ABC1 family protein MCP2 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q3MIX3 | ADCK5 | Uncharacterized aarF domain-containing protein kinase 5 | Homo sapiens (Human) | SS |
| Q86TW2 | ADCK1 | AarF domain-containing protein kinase 1 | Homo sapiens (Human) | SS |
| Q9MA15 | ABC1K3 | Protein ACTIVITY OF BC1 COMPLEX KINASE 3, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAARSLWRTR | TKLLVVGTAL | CGGSGAAFIA | SSDDPSTTLK | LCTSIPVRLY | RNTVTAASIA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FDYEYSLLGL | AEGSSERAKV | KHEVHLRSAQ | KLQELCFKNG | GIYIKLGQHI | GQLEYLVPEE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YVRTMRESML | NKCPISSYEQ | VCEVFKKEVG | EMPDQVFAEF | DPVPIASASL | AQVHVARTHD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GKKVAVKVQH | AHMTDTAAAD | TAAVGVLVNT | LHRIFPSFDY | RWLLDEMSES | LPKELDFLVE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AKNNEKCLDN | FRKLSPHIAE | YVYAPTIYWN | LSTSKLLTME | FMDGAQVNDV | DKIRKLGIQP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YEVSKLVSQT | FAEMMFKHGF | VHCDPHAANL | IVRPDPSGKR | NIYGKRKPQL | VILDHGLYKE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LDFNTRFNYA | SLWKALVFSD | AKAIKEHSEK | LGAGDDLYVL | FAGILTMRPW | KQVIDTSVDH |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LVIQGNKEDV | SELQMYASQY | FSEISELLRR | LPRVILLMLK | TNDCLRSVNN | ELMQGSSLES |
| 490 | 500 | 510 | 520 | 530 | |
| FLIIGKVSSQ | AVLEAKRAEK | KSLMKWLKVW | FEGFSVEARL | WVMQFALWIL | QVRKSLTL |