O04161

PR
Gene name
AMT1-2
Protein name
Ammonium transporter 1 member 2
Names
LeAMT12
Species
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O04161

Entry ID Method Resolution Chain Position Source
AF-O04161-F1 Predicted AlphaFoldDB

No variants for O04161

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O04161

No associated diseases with O04161

4 regional properties for O04161

Type Name Position InterPro Accession
conserved_site Aldo/keto reductase, conserved site 39 - 56 IPR018170-1
conserved_site Aldo/keto reductase, conserved site 145 - 162 IPR018170-2
conserved_site Aldo/keto reductase, conserved site 261 - 276 IPR018170-3
domain NADP-dependent oxidoreductase domain 16 - 289 IPR023210

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
ammonium transmembrane transporter activity Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.

2 GO annotations of biological process

Name Definition
ammonium homeostasis Any biological process involved in the maintenance of an internal steady state of ammonium.
ammonium transmembrane transport The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6K9G1 AMT1-2 Ammonium transporter 1 member 2 Oryza sativa subsp japonica (Rice) PR
Q7XQ12 AMT1-1 Ammonium transporter 1 member 1 Oryza sativa subsp japonica (Rice) PR
Q21565 amt-3 Putative ammonium transporter 3 Caenorhabditis elegans PR
10 20 30 40 50 60
MASAMTCSAA ELFPHLGSSA NATAAAEFIC SRFSAVSEYL TNTTYAVDTT YLLFSAYLVF
70 80 90 100 110 120
AMQLGFAMLC AGSVRAKNTM NIMLTNVLDA AAGGFSYYLF GFAFAFGAPS NGFIGKHFFG
130 140 150 160 170 180
LKEFPSQAFD YSYFLYQWAF AIAAAGITSG SIAERTQFVA YLIYSSFLTG FVYPIVSHWF
190 200 210 220 230 240
WSGDGWASAS KTDGNLLLRF GVIDFAGSGV VHMVGGIAGL WGAFIEGPRI GRFDRSGRSV
250 260 270 280 290 300
ALRGHSASLV VLGTFLLWFG WYGFNPGSFL TILKSYDHTI RGTYYGQWSA IGRTAVTTTL
310 320 330 340 350 360
AGCTAALTTL FCKRLLVAHW NVVDVCNGLL GGFAAITSGC AVVEPWAAIV CGFIAAWVLI
370 380 390 400 410 420
GFNALAAKLK YDDPLEAAQL HGGCGSWGII FTGLFAKKEY VNEVYPGFPN RPYGLFMGGG
430 440 450 460 470 480
GKLLGAQVIQ VVVIIGWVSV TMGPLFYLLH KFKLLRISRD DETAGMDLTR HGGFAYIYHD
490 500 510
EDEGSSMPGF KMTRVEPTNT STPDHQNRSV NVVV