K9JA28

PR
Gene name
IFNLR1 (IL28RA)
Protein name
Interferon lambda receptor 1
Names
IFN-lambda R1, Cytokine receptor class-II member 12, Cytokine receptor family 2 member 12, CRF2-12, Interleukin-28 receptor subunit alpha, IL-28 receptor subunit alpha, IL-28R-alpha, IL-28RA
Species
Gallus gallus (Chicken)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

267-567 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for K9JA28

Entry ID Method Resolution Chain Position Source
AF-K9JA28-F1 Predicted AlphaFoldDB

4 variants for K9JA28

Variant ID(s) Position Change Description Diseaes Association Provenance
rs733638320 199 S>P No Ensembl
rs312348354 275 F>L No Ensembl
rs316514630 432 G>R No Ensembl
rs739616479 463 H>P No Ensembl

No associated diseases with K9JA28

1 regional properties for K9JA28

Type Name Position InterPro Accession
domain Peptidase M20, dimerisation domain 242 - 334 IPR011650

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass type I membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8CGK5 Ifnlr1 Interferon lambda receptor 1 Mus musculus (Mouse) PR
10 20 30 40 50 60
MSAWRIRVLA TLCFLWQPRV HGQLPPPQNV TLLSKDFDMI LTWTPGEGSP PDVLYTVRYE
70 80 90 100 110 120
SKTRMDKWIK VPHCRNIHSV SCNLTCVIPN FFIKFRAQVK ATSGRFHSPW VKSQFKEYHL
130 140 150 160 170 180
DVELAPPLLN VNVKENVIHV NATFPMAICV ESLPWMYDFN LWEAGSEDKK QYKSIFRKKA
190 200 210 220 230 240
VTIDTTALRG NYCFNARSSI QSIDFKHSKF SQPVCMQLNY EGEWKFPFSA TIPVFVLLIL
250 260 270 280 290 300
LTSASIIWLL KQDAKHKKMP QTLDLSNCKI AGPTFCCELR ENEFLTDCLI CTDKPMSQGK
310 320 330 340 350 360
KNKTLAQNNQ MWMASFLPSS SSEEEEEEEE EDSSSFIPYT EMLQFPRKHF NFQTPRTADA
370 380 390 400 410 420
ETILDSTSGV LSVVGGSTLD LSALGFSFFP IRKNEMDTSG SQGNEKASHS HSSSLGRISL
430 440 450 460 470 480
TDVRFPGPRE HGQHGTDSND CLEVSLLHTL MNSSCTRLPA DEHCLYKKDH DFTICYQKPT
490 500 510 520 530 540
LDQPVQVSEN PLLNEDPSME KFIYLQTLQV AEDEGFASDC DSGNFTEGTP PASTVLSDEL
550 560
RISDMEKRYD KKFKFKGYQH SHYMRRS