H9N290

PR
Gene name
ndmB
Protein name
Methylxanthine N3-demethylase NdmB
Names
3-methylxanthine demethylase
Species
Pseudomonas putida (Arthrobacter siderocapsulatus)
KEGG Pathway
ag:AFD03117
EC number
1.14.13.179: With NADH or NADPH as one donor, and incorporation of one atom of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

181-251 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for H9N290

Entry ID Method Resolution Chain Position Source
6ICL X-ray 210 A A 1-355 PDB
AF-H9N290-F1 Predicted AlphaFoldDB

No variants for H9N290

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for H9N290

No associated diseases with H9N290

2 regional properties for H9N290

Type Name Position InterPro Accession
domain Rieske [2Fe-2S] iron-sulphur domain 19 - 131 IPR017941
domain Vanillate O-demethylase oxygenase-like, C-terminal catalytic domain 164 - 331 IPR044043

Functions

Description
EC Number 1.14.13.179 With NADH or NADPH as one donor, and incorporation of one atom of oxygen
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
2 iron, 2 sulfur cluster binding Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
demethylase activity Catalysis of the removal of a methyl group from a substrate.
metal ion binding Binding to a metal ion.
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

1 GO annotations of biological process

Name Definition
alkaloid catabolic process The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKEQLKPLLE DKTYLRHFWH PVCTLNEFER ANASGHGPMG VTLLGEKLVL ARLNSKIIAA
70 80 90 100 110 120
ADRCAHRSAQ LSIGRVCSNA GKDYLECPYH GWRYDEAGAC QLIPACPDKS ISPRAKISSF
130 140 150 160 170 180
DCEVKYDIVW VRLDNSFDCT QIPYLSDFDN PDMQVIVADS YIWETVAERR WENFTDFSHF
190 200 210 220 230 240
AFVHPGTLYD PFFASHPTVY VNRVDGELQF KLAPPREMKG IPPEAPMGDF TYRCTMPYSV
250 260 270 280 290 300
NLEIKLWKDD SRFVLWTTAS PVDNKSCRNF MIIVREKDNQ PDHMHLAFQK RVLDEDQPVI
310 320 330 340 350
ESQWPLEIQT SEVSVATDKI SVQFRKWHKE LSLSAVEGRE AFRDSVLTNV IEEEQ