Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for H2DH20

Entry ID Method Resolution Chain Position Source
AF-H2DH20-F1 Predicted AlphaFoldDB

No variants for H2DH20

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for H2DH20

No associated diseases with H2DH20

2 regional properties for H2DH20

Type Name Position InterPro Accession
domain Uracil-DNA glycosylase-like 56 - 216 IPR005122
active_site Uracil-DNA glycosylase, active site 64 - 73 IPR018085

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

4 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
iron ion binding Binding to an iron (Fe) ion.
monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MELQFPLFSI FFVTILFFFL FKKSSKTTKN LPPGPRKLPI IGNILELAGE VQHRVLAELS
70 80 90 100 110 120
QKHGPIMHLQ LAEISAIVVS SSKVAKEVLK THDLAFSDRA QLQLSKIILK GCKDVVFNDY
130 140 150 160 170 180
DDYWRQMRKI CTVELLTANK VNSFRAIRED EAWNLVESIK TSLDSPVNLT HKFTSLTNAI
190 200 210 220 230 240
TCRAAIGERS KYQDELVHLI ELMAALGGGF DIADLFPSYK FLHFLSGLRS KLEKVRKRLD
250 260 270 280 290 300
DIFYNILKEH EEKRAKTKNS DGRVAGEEDL VDVLLRVQEK GGLQFPISSN NIQGIICDML
310 320 330 340 350 360
TAGTDTASTA LDWAMSELVR YPSVLHKAQA EVREAFKGKT KIHEDDVQGL SYLKLVIKET
370 380 390 400 410 420
LRLHPPAPLL LPKECREQCV IEGYTIPVRT KLIVNAWAIG RDPEYWVNAE SFDPERFSNK
430 440 450 460 470 480
SIDYNGTNLN YIPFGAGRRS CPGIAFGIAT IELPLALLLY HFNWGMPGGI KPSALDMNEV
490 500
LGATLKRKTN LLLSATSYTP NEDSS