H1AFJ7

PR
Gene name
scnn1g (enacgamma)
Protein name
Amiloride-sensitive sodium channel subunit gamma
Names
Epithelial Na(+) channel subunit gamma, Gamma-ENaC, Gamma-NaCH, Nonvoltage-gated sodium channel 1 subunit gamma, SCNEG
Species
Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

552-653 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for H1AFJ7

Entry ID Method Resolution Chain Position Source
AF-H1AFJ7-F1 Predicted AlphaFoldDB

No variants for H1AFJ7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for H1AFJ7

No associated diseases with H1AFJ7

1 regional properties for H1AFJ7

Type Name Position InterPro Accession
conserved_site Epithelial sodium channel, conserved site 396 - 416 IPR020903

Functions

Description
EC Number
Subcellular Localization
  • Apical cell membrane ; Multi-pass membrane protein
  • Apical membrane of epithelial cells
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
apical plasma membrane The region of the plasma membrane located at the apical end of the cell.
sodium channel complex An ion channel complex through which sodium ions pass.

1 GO annotations of molecular function

Name Definition
ligand-gated sodium channel activity Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

3 GO annotations of biological process

Name Definition
response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
sensory perception of taste The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.
sodium ion transmembrane transport A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGHGRRISES IKKQLPVTGP EAPTVKNLMD WYLNNTNTHG CRRIAVSRGY LRRWIWICFT
70 80 90 100 110 120
VSSVGMIFWQ WTLLLMSYYT VSVSVTVQFQ TLPFPAVTIC NINPYRKNAT SALLEELDKQ
130 140 150 160 170 180
TKLILKELYT SCTGCSNRKL RSVLLNEAPE EDSGVAKLLQ DMPLMKFEVI KEDHVIVSEL
190 200 210 220 230 240
SSNRQYRINN TFITRMYNNM DLATVGEQVG FKICDANKSN CIIYTFNSGV TAILEWYRLN
250 260 270 280 290 300
YLNIMAQIPN EKKLEMGYSA DDLIVTCMYD GQSCDSRNFT LFQHPLHGNC YTFNSGDDGN
310 320 330 340 350 360
ILQTLTGGSE YGLKLTLYLE NDDYNPYLFT SMGAKIIVHD QTEYPLVDDV GLEIQTATET
370 380 390 400 410 420
LIGLQVTTSA KLSKPYSDCT MDGSDVLEQN LYNTSYSLQI CLHSCFQTEM ISNCGCAYYE
430 440 450 460 470 480
QPLPSGAEYC YYEKYPGWIY CYYQLQDKFV NERLACQDIC KETCNSKDWD LTKSLARWPS
490 500 510 520 530 540
VASKDWVLNL LNWERGLNNT LNKNDLASIA IFYQDLNLRS LSESPANSIA TLLSNMGGQL
550 560 570 580 590 600
GLWMSCSIVC FLEMWEVFLV DILTIIARYW LHRGRQWWRK RKERQMQQPS PPDHDTGHHN
610 620 630 640 650
PVCIDDEDPP TFHTAMQLPC VQTGPVPSTP PPQYNALRIQ SVFDEQVSDT EVN