G5EB76

PR
Gene name
sidA
Protein name
L-ornithine N(5)-monooxygenase
Names
OMO, L-ornithine N(5)-oxygenase, Siderophore biosynthesis protein A
Species
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
KEGG Pathway
ani:AN5823.2
EC number
1.14.13.196: With NADH or NADPH as one donor, and incorporation of one atom of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-56 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for G5EB76

Entry ID Method Resolution Chain Position Source
AF-G5EB76-F1 Predicted AlphaFoldDB

No variants for G5EB76

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for G5EB76

No associated diseases with G5EB76

9 regional properties for G5EB76

Type Name Position InterPro Accession
domain RNA polymerase sigma-70 114 - 127 IPR000943-1
domain RNA polymerase sigma-70 138 - 146 IPR000943-2
domain RNA polymerase sigma-70 262 - 274 IPR000943-3
domain RNA polymerase sigma-70 283 - 309 IPR000943-4
domain RNA polymerase sigma-70 region 3 169 - 245 IPR007624
domain RNA polymerase sigma-70 region 2 90 - 159 IPR007627
domain RNA polymerase sigma-70 region 4 258 - 311 IPR007630
domain RNA polymerase sigma-70 region 1.2 25 - 58 IPR009042
domain RNA polymerase sigma-70 like domain 86 - 311 IPR014284

Functions

Description
EC Number 1.14.13.196 With NADH or NADPH as one donor, and incorporation of one atom of oxygen
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
ornithine N5-monooxygenase activity Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O.

5 GO annotations of biological process

Name Definition
cellular iron ion homeostasis Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
cellular response to iron ion starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.
cellular response to oxidative stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
ferrichrome biosynthetic process The chemical reactions and pathways resulting in the formation of a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.
siderophore biosynthetic process The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEPLQRKSEL DFQSYRKMPL AQQRTQRLKP TSPEELHDLI CVGFGPASLA IAIALHDALD
70 80 90 100 110 120
PCLNKCAPTS GWQPKVAFLE RQKQFAWHSG MLVPGSRMQI SFIKDLATLR DPRSSFTFLN
130 140 150 160 170 180
YLHQKDRLIH FTNLSTFLPA RMEFEDYMRW CANQFSDVVT YGEEVIEVLP GKSSPDSPVV
190 200 210 220 230 240
DYFTVLSRNV ETGEISSRSA RKVVLALGGT AKLPAELPQD PRIMHSSKYC TALPNLLKDN
250 260 270 280 290 300
NEPYNIAVLG SGQSAAEIFH DLQKRYPNSR TSLIMRDTAM RPSDDSPFVN EVFNPERTDK
310 320 330 340 350 360
FYNLSAAERE RSLKADKATN YSVVRLELIE EIYHDMYLQR VKNPDETQWQ HRILPSRKIT
370 380 390 400 410 420
RVEHYGPNKR MRVHVRAVKD GKDSLIGDGK EVLEVDALMV ATGYNRNAHE QLLSKVQYLR
430 440 450 460 470 480
PATQDRWTPS RDYRVDLDRS KVSAGAGIWL QGSNEQTHGL SDSLLSVLAT RGGEMVESIF
490
GEQLESAAVP DTRFRAML