G3KIM4
Gene name |
lcdA |
Protein name |
Lactoyl-CoA dehydratase subunit alpha |
Names |
(R)-lactyl-CoA dehydratase component E II, 2-hydroxybutyroyl-CoA dehydratase |
Species |
Anaerotignum propionicum (Clostridium propionicum) |
KEGG Pathway |
ag:AEM62994 |
EC number |
4.2.1.54: Hydro-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for G3KIM4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-G3KIM4-F1 | Predicted | AlphaFoldDB |
No variants for G3KIM4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for G3KIM4 | |||||
No associated diseases with G3KIM4
No regional properties for G3KIM4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for G3KIM4 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 4.2.1.54 | Hydro-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| 4 iron, 4 sulfur cluster binding | Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. |
| lactoyl-CoA dehydratase activity | Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O. |
| metal ion binding | Binding to a metal ion. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSLTQGMKAK | QLLAYFQGKA | DQDAREAKAR | GELVCWSASV | APPEFCVTMG | IAMIYPETHA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AGIGARKGAM | DMLEVADRKG | YNVDCCSYGR | VNMGYMECLK | EAAITGVKPE | VLVNSPAADV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PLPDLVITCN | NICNTLLKWY | ENLAAELDIP | CIVIDVPFNH | TMPIPEYAKA | YIADQFRNAI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SQLEVICGRP | FDWKKFKEVK | DQTQRSVYHW | NRIAEMAKYK | PSPLNGFDLF | NYMALIVACR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SLDYAEITFK | AFADELEENL | KAGIYAFKGA | EKTRFQWEGI | AVWPHLGHTF | KSMKNLNSIM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TGTAYPALWD | LHYDANDESM | HSMAEAYTRI | YINTCLQNKV | EVLLGIMEKG | QVDGTVYHLN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RSCKLMSFLN | VETAEIIKEK | NGLPYVSIDG | DQTDPRVFSP | AQFDTRVQAL | VEMMEANMAA |
| AE |