Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for G2TRT1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-G2TRT1-F1 | Predicted | AlphaFoldDB |
No variants for G2TRT1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for G2TRT1 | |||||
No associated diseases with G2TRT1
1 regional properties for G2TRT1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zn(2)Cys(6) fungal-type DNA-binding domain | 28 - 71 | IPR001138 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. |
| zinc ion binding | Binding to a zinc ion (Zn). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| positive regulation of transcription by RNA polymerase II | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MHLSKASFLF | DCSRFILNFH | ERCLKNGVRT | KKACVICRSK | KQKCDGQLPC | LYCKKYEYQC |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AYEGQATSTC | NSEASLFNDA | NFKIGSDYRS | KRIKVVSDTN | NNKEDGDGKL | SFTQCNPRMD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IHHEAENFTA | MVPYYEPKKF | RFFYENSAIV | FPRIYVFIYF | EEVHPIFSMF | DQKAMEKKIQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FLWDNKSTDS | CSEYVVISVK | GKLVEHITQV | LESSLSTTIL | SSIQLTVCWV | LRTIYLHATT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RPHLSWIASS | VSMHYAEIVG | LHQEITAEYG | TRGIELTNIT | TQMVEEDGPA | YQLVLLFKII |
| 310 | 320 | 330 | 340 | 350 | 360 |
| MEYQIISEDS | RFVYLQAFQR | LDQLCDIHSP | ALVLLKATVC | FHLYRNLFLA | RIKPFCVIVS |
| 370 | 380 | ||||
| ILFSVIDRAL | ESCKQLVSQR | KAW |