G0SC29

PR
Gene name
CTHT_0055700
Protein name
Ribosome assembly protein 4
Names
Notchless protein homolog 1, Ribosome biogenesis factor RSA4
Species
Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) (Thermochaetoides thermophila)
KEGG Pathway
cthr:CTHT_0055700
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

12 structures for G0SC29

Entry ID Method Resolution Chain Position Source
4WJS X-ray 180 A A 33-517 PDB
6QTA X-ray 189 A B 30-128 PDB
8PV1 EM 256 A Ch 1-517 PDB
8PV3 EM 280 A Ch 1-517 PDB
8PV4 EM 290 A Ch 1-517 PDB
8PV5 EM 286 A Ch 1-517 PDB
8PV6 EM 294 A Ch 1-517 PDB
8PV7 EM 212 A Ch 1-517 PDB
8PV8 EM 291 A Ch 1-517 PDB
8PVK EM 255 A Ch 1-517 PDB
8PVL EM 219 A Ch 1-517 PDB
AF-G0SC29-F1 Predicted AlphaFoldDB

No variants for G0SC29

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for G0SC29

No associated diseases with G0SC29

9 regional properties for G0SC29

Type Name Position InterPro Accession
repeat WD40 repeat 135 - 316 IPR001680-1
repeat WD40 repeat 310 - 388 IPR001680-2
repeat WD40 repeat 393 - 517 IPR001680-3
conserved_site WD40 repeat, conserved site 162 - 176 IPR019775-1
conserved_site WD40 repeat, conserved site 419 - 433 IPR019775-2
conserved_site WD40 repeat, conserved site 461 - 475 IPR019775-3
repeat G-protein beta WD-40 repeat 162 - 176 IPR020472-1
repeat G-protein beta WD-40 repeat 294 - 308 IPR020472-2
repeat G-protein beta WD-40 repeat 461 - 475 IPR020472-3

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
protein-RNA complex remodeling The acquisition, loss, or modification of macromolecules within a protein-RNA complex, resulting in the alteration of an existing complex.
ribosomal large subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATLAPPPSK RQRREEIQRT QTQQDVTPLV ATDLGSFKAN FIDSDGNQMT DVVEINFADA
70 80 90 100 110 120
TEKNISNLLN TLLGRDREEF TPYRFRIHIP GKDLIIDQYP NDLLSLLQKH GVTNPFETTI
130 140 150 160 170 180
TLSAEPQAIF KVHAVSRLAH RIPGHGQPIL SCQFSPVSSS RLATGSGDNT ARIWDTDSGT
190 200 210 220 230 240
PKFTLKGHTG WVLGVSWSPD GKYLATCSMD TTVRVWDPES GKQVNQEFRG HAKWVLALAW
250 260 270 280 290 300
QPYHLWRDGT ARLASASKDC TVRIWLVNTG RTEHVLSGHK GSVSCVKWGG TDLIYTGSHD
310 320 330 340 350 360
RSVRVWDAVK GTLVHNFTAH GHWVNHIALS SDHVLRTAYH DHTKEVPGTE EERRAKAKER
370 380 390 400 410 420
FEKAAKIKGK VAERLVSASD DFTMYLWDPT NNGSKPVARL LGHQNKVNHV QFSPDGTLIA
430 440 450 460 470 480
SAGWDNSTKL WNARDGKFIK NLRGHVAPVY QCAWSADSRL VVTGSKDCTL KVWNVRTGKL
490 500 510
AMDLPGHEDE VYAVDWAADG ELVASGGKDK AVRTWRN