G0S616

PR
Gene name
CTHT_0025680
Protein name
Ribosome assembly factor mrt4
Names
mRNA turnover protein 4
Species
Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) (Thermochaetoides thermophila)
KEGG Pathway
cthr:CTHT_0025680
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

209-270 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

19 structures for G0S616

Entry ID Method Resolution Chain Position Source
4NWB X-ray 180 A A 1-270 PDB
8I9T EM 360 A CF 1-270 PDB
8I9V EM 310 A CF 1-270 PDB
8I9W EM 310 A CF 1-270 PDB
8I9X EM 280 A CF 1-270 PDB
8I9Y EM 310 A CF 1-270 PDB
8I9Z EM 270 A CF 1-270 PDB
8IA0 EM 270 A CF 1-270 PDB
8PV1 EM 256 A CF 1-270 PDB
8PV2 EM 263 A CF 1-270 PDB
8PV3 EM 280 A CF 1-270 PDB
8PV4 EM 290 A CF 1-270 PDB
8PV5 EM 286 A CF 1-270 PDB
8PV6 EM 294 A CF 1-270 PDB
8PV7 EM 212 A CF 1-270 PDB
8PV8 EM 291 A CF 1-270 PDB
8PVK EM 255 A CF 1-270 PDB
8PVL EM 219 A CF 1-270 PDB
AF-G0S616-F1 Predicted AlphaFoldDB

No variants for G0S616

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for G0S616

No associated diseases with G0S616

1 regional properties for G0S616

Type Name Position InterPro Accession
domain 60S ribosomal protein L10P, insertion domain 125 - 214 IPR040637

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
  • Cytoplasm
  • Shuttles between the nucleus and the cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.
ribosome An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
ribosomal large subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPKSKRARVY HLTQVNKKGR EAKERLFSNI RETIPKYQHC FVFSVDNMRN NYLKDVRHEL
70 80 90 100 110 120
NDCRIFFGKT KLMARALGTT PEEEQADGLH RLTRYLTGTV GLLFTNRDPA DIESYFSNLS
130 140 150 160 170 180
QVDFARAGTV APRTVTVPPG IVYSTGGEVP PEHDVPVSHT LEPELRRLGM PVRMIKGKVC
190 200 210 220 230 240
LGDEKGEASE GYTICKEGEV LDSRQTRLLK LFSICLSEFK VSLLGYWSSA SGEVTELEAG
250 260
KTRPKREGNR RQAMNGDEMD EDQSSDEDSD