F4KGY6
Gene name |
RVE1 (At5g17300, MKP11.15) |
Protein name |
Protein REVEILLE 1 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G17300 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for F4KGY6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-F4KGY6-F1 | Predicted | AlphaFoldDB |
26 variants for F4KGY6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH14061301 | 2 | A>T | No | 1000Genomes | |
| ENSVATH06981151 | 23 | E>D | No | 1000Genomes | |
| tmp_5_5691953_G_A | 24 | T>I | No | 1000Genomes | |
| ENSVATH06981150 | 26 | D>N | No | 1000Genomes | |
| ENSVATH03067545 | 40 | D>H | No | 1000Genomes | |
| ENSVATH06981148 | 79 | R>Q | No | 1000Genomes | |
| ENSVATH10804747 | 84 | V>L | No | 1000Genomes | |
| ENSVATH00627058 | 85 | G>A | No | 1000Genomes | |
| tmp_5_5691361_C_G | 112 | G>R | No | 1000Genomes | |
| ENSVATH10804745 | 149 | S>Y | No | 1000Genomes | |
| ENSVATH03067521 | 165 | V>F | No | 1000Genomes | |
| ENSVATH03067520 | 201 | P>L | No | 1000Genomes | |
| tmp_5_5691091_C_G | 202 | E>Q | No | 1000Genomes | |
| tmp_5_5691082_C_T | 205 | E>K | No | 1000Genomes | |
| ENSVATH14061297 | 218 | L>F | No | 1000Genomes | |
| ENSVATH06981144 | 221 | E>K | No | 1000Genomes | |
| tmp_5_5690850_A_C | 250 | L>R | No | 1000Genomes | |
| ENSVATH03067518 | 276 | I>R | No | 1000Genomes | |
| tmp_5_5690760_T_A | 280 | Q>L | No | 1000Genomes | |
| ENSVATH06981143 | 283 | L>F | No | 1000Genomes | |
| ENSVATH06981142 | 308 | V>F | No | 1000Genomes | |
| tmp_5_5690655_G_C | 315 | T>S | No | 1000Genomes | |
| ENSVATH03067517 | 328 | T>M | No | 1000Genomes | |
| ENSVATH06981140 | 331 | T>I | No | 1000Genomes | |
| ENSVATH00627053 | 352 | S>Y | No | 1000Genomes | |
| ENSVATH10804706 | 382 | E>A | No | 1000Genomes |
No associated diseases with F4KGY6
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| auxin-activated signaling pathway | The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription. |
| circadian rhythm | Any biological process in an organism that recurs with a regularity of approximately 24 hours. |
| regulation of auxin biosynthetic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q99543 | DNAJC2 | DnaJ homolog subfamily C member 2 | Homo sapiens (Human) | PR |
| P54103 | Dnajc2 | DnaJ homolog subfamily C member 2 | Mus musculus (Mouse) | PR |
| Q7TQ20 | Dnajc2 | DnaJ homolog subfamily C member 2 | Rattus norvegicus (Rat) | PR |
| P34454 | F54F2.9 | Uncharacterized protein F54F2.9 | Caenorhabditis elegans | PR |
| F4K5X6 | RVE2 | Protein REVEILLE 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q6NWJ4 | dnajc2 | DnaJ homolog subfamily C member 2 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASSPLTANV | QGTNASLRNR | DEETADKQIQ | FNDQSFGGND | YAPKVRKPYT | ITKERERWTD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EEHKKFVEAL | KLYGRAWRRI | EEHVGSKTAV | QIRSHAQKFF | SKVAREATGG | DGSSVEPIVI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PPPRPKRKPA | HPYPRKFGNE | ADQTSRSVSP | SERDTQSPTS | VLSTVGSEAL | CSLDSSSPNR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SLSPVSSASP | PAALTTTANA | PEELETLKLE | LFPSERLLNR | ESSIKEPTKQ | SLKLFGKTVL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VSDSGMSSSL | TTSTYCKSPI | QPLPRKLSSS | KTLPIIRNSQ | EELLSCWIQV | PLKQEDVENR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| CLDSGKAVQN | EGSSTGSNTG | SVDDTGHTEK | TTEPETMLCQ | WEFKPSERSA | FSELRRTNSE |
| 370 | 380 | ||||
| SNSRGFGPYK | KRKMVTEEEE | HEIHLHL |