F4KEW8
Gene name |
NET4A |
Protein name |
Protein NETWORKED 4A |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G58320 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for F4KEW8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-F4KEW8-F1 | Predicted | AlphaFoldDB |
22 variants for F4KEW8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH03447862 | 99 | G>V | No | 1000Genomes | |
| ENSVATH03447863 | 125 | S>T | No | 1000Genomes | |
| ENSVATH12840223 | 206 | D>E | No | 1000Genomes | |
| tmp_5_23578649_T_A | 229 | L>M | No | 1000Genomes | |
| tmp_5_23578700_C_T | 246 | L>F | No | 1000Genomes | |
| tmp_5_23578779_G_A | 272 | S>N | No | 1000Genomes | |
| ENSVATH07444765 | 289 | G>R | No | 1000Genomes | |
| tmp_5_23578985_G_C | 341 | D>H | No | 1000Genomes | |
| tmp_5_23578996_G_C | 344 | E>D | No | 1000Genomes | |
| tmp_5_23579054_G_A | 364 | V>M | No | 1000Genomes | |
| ENSVATH00740726 | 409 | D>E | No | 1000Genomes | |
| tmp_5_23579232_A_T | 423 | Q>L | No | 1000Genomes | |
| ENSVATH03447868 | 438 | R>I | No | 1000Genomes | |
| tmp_5_23579316_A_C | 451 | K>T | No | 1000Genomes | |
| ENSVATH07444767 | 463 | K>N | No | 1000Genomes | |
| tmp_5_23579354_G_A | 464 | V>I | No | 1000Genomes | |
| ENSVATH03447869 | 467 | G>E | No | 1000Genomes | |
| tmp_5_23579376_A_G | 471 | E>G | No | 1000Genomes | |
| ENSVATH00740727 | 476 | K>E | No | 1000Genomes | |
| tmp_5_23579392_G_T | 476 | K>N | No | 1000Genomes | |
| tmp_5_23579394_T_G | 477 | V>G | No | 1000Genomes | |
| tmp_5_23579601_G_T | 546 | G>V | No | 1000Genomes |
No associated diseases with F4KEW8
1 regional properties for F4KEW8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Protein Networked (NET), actin-binding (NAB) domain | 21 - 101 | IPR011684 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| vacuolar membrane | The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| actin binding | Binding to monomeric or multimeric forms of actin, including actin filaments. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDYDLLRSKK | SIKRVESTKS | NPWWWDSHIG | LKNSKWLENN | LDEMDRSVKR | MVKLIEEDAD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SFAKKAEMYY | QSRPELIALV | DEFHRMYRAL | AERYENITGE | LRKGSPLELQ | SQGSGLSDIS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ASDLSALWTS | NEVNRLGRPP | SGRRAPGFEY | FLGNGGLPSD | LYHKDGDDSA | SITDSELESD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DSSVTNYPGY | VSIGSDFQSL | SKRIMDLEIE | LREAKERLRM | QLEGNTESLL | PRVKSETKFV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DFPAKLAACE | QELKDVNEKL | QNSEDQIYIL | KSQLARYLPS | GLDDEQSEGA | ASTQELDIET |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LSEELRITSL | RLREAEKQNG | IMRKEVEKSK | SDDAKLKSLQ | DMLESAQKEA | AAWKSKASAD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KREVVKLLDR | ISMLKSSLAG | RDHEIRDLKT | ALSDAEEKIF | PEKAQVKADI | AKLLEEKIHR |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DDQFKELEAN | VRYLEDERRK | VNNEKIEEEE | KLKSEIEVLT | LEKVEKGRCI | ETLSRKVSEL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ESEISRLGSE | IKARDDRTME | MEKEVEKQRR | ELEEVAEEKR | EVIRQLCFSL | DYSRDEYKRL |
| 550 | |||||
| RIAFSGHPPT | RPSSILAS |