F4JLK2
PR
Gene name |
SPS4 |
Protein name |
Sucrose-phosphate synthase 4 |
Names |
Sucrose phosphate synthase 4F, AtSPS4F, Sucrose phosphate synthase C, UDP-glucose-fructose-phosphate glucosyltransferase |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G10120 |
EC number |
2.4.1.14: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for F4JLK2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-F4JLK2-F1 | Predicted | AlphaFoldDB |
64 variants for F4JLK2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_4_6315081_G_A | 17 | V>I | No | 1000Genomes | |
| tmp_4_6315183_A_T | 51 | M>L | No | 1000Genomes | |
| tmp_4_6315201_C_A | 57 | Q>K | No | 1000Genomes | |
| tmp_4_6315239_A_C | 69 | E>D | No | 1000Genomes | |
| ENSVATH06600005 | 125 | L>I | No | 1000Genomes | |
| tmp_4_6315727_C_T | 147 | L>F | No | 1000Genomes | |
| tmp_4_6315736_G_A | 150 | G>R | No | 1000Genomes | |
| ENSVATH06600007 | 158 | E>D | No | 1000Genomes | |
| ENSVATH06600008 | 166 | T>I | No | 1000Genomes | |
| tmp_4_6315791_T_A | 168 | L>H | No | 1000Genomes | |
| ENSVATH14118564 | 177 | R>H | No | 1000Genomes | |
| tmp_4_6315866_G_A | 193 | R>Q | No | 1000Genomes | |
| tmp_4_6316216_C_G | 236 | T>S | No | 1000Genomes | |
| ENSVATH06600019 | 259 | G>A | No | 1000Genomes | |
| ENSVATH11420620 | 287 | R>W | No | 1000Genomes | |
| tmp_4_6316374_A_G | 289 | K>E | No | 1000Genomes | |
| tmp_4_6316653_G_A | 350 | A>T | No | 1000Genomes | |
| tmp_4_6316671_G_C | 356 | V>L | No | 1000Genomes | |
| ENSVATH02770949 | 413 | D>E | No | 1000Genomes | |
| tmp_4_6317152_G_A | 460 | V>I | No | 1000Genomes | |
| ENSVATH00485127 | 470 | G>V | No | 1000Genomes | |
| ENSVATH06600029 | 476 | I>L | No | 1000Genomes | |
| ENSVATH02770969 | 499 | S>L | No | 1000Genomes | |
| tmp_4_6317417_T_G | 510 | S>A | No | 1000Genomes | |
| tmp_4_6317447_A_T | 520 | T>S | No | 1000Genomes | |
| ENSVATH14118668 | 528 | C>F | No | 1000Genomes | |
| tmp_4_6318382_G_A | 644 | D>N | No | 1000Genomes | |
| tmp_4_6318419_T_G | 656 | L>R | No | 1000Genomes | |
| tmp_4_6318509_G_A | 686 | R>H | No | 1000Genomes | |
| tmp_4_6318565_G_A | 705 | D>N | No | 1000Genomes | |
| ENSVATH00485152 | 735 | T>I | No | 1000Genomes | |
| ENSVATH00485153 | 736 | L>F | No | 1000Genomes | |
| tmp_4_6318733_G_A | 761 | G>S | No | 1000Genomes | |
| ENSVATH00485154 | 762 | C>R | No | 1000Genomes | |
| ENSVATH00485155 | 763 | S>P | No | 1000Genomes | |
| ENSVATH00485156 | 769 | P>R | No | 1000Genomes | |
| tmp_4_6318773_T_C | 774 | M>T | No | 1000Genomes | |
| tmp_4_6318778_T_A | 776 | F>I | No | 1000Genomes | |
| tmp_4_6318781_G_T | 777 | V>L | No | 1000Genomes | |
| ENSVATH11420863 | 782 | S>P | No | 1000Genomes | |
| tmp_4_6318816_C_G | 788 | N>K | No | 1000Genomes | |
| ENSVATH00485157 | 791 | A>P | No | 1000Genomes | |
| ENSVATH00485157 | 791 | A>S | No | 1000Genomes | |
| tmp_4_6318835_G_A | 795 | E>K | No | 1000Genomes | |
| tmp_4_6318917_G_C | 822 | S>T | No | 1000Genomes | |
| tmp_4_6318932_T_A | 827 | V>E | No | 1000Genomes | |
| ENSVATH00485159 | 828 | D>E | No | 1000Genomes | |
| ENSVATH06600055 | 830 | T>M | No | 1000Genomes | |
| tmp_4_6318969_T_A | 839 | D>E | No | 1000Genomes | |
| ENSVATH06600057 | 862 | A>E | No | 1000Genomes | |
| ENSVATH00485161 | 885 | I>V | No | 1000Genomes | |
| ENSVATH00485162 | 891 | A>T | No | 1000Genomes | |
| tmp_4_6319126_G_A | 892 | E>K | No | 1000Genomes | |
| tmp_4_6319347_A_T | 939 | T>S | No | 1000Genomes | |
| ENSVATH06600061 | 940 | H>Q | No | 1000Genomes | |
| ENSVATH14118669 | 951 | C>R | No | 1000Genomes | |
| ENSVATH00485169 | 998 | K>E | No | 1000Genomes | |
| ENSVATH00485169 | 998 | K>Q | No | 1000Genomes | |
| ENSVATH11420956 | 1006 | E>G | No | 1000Genomes | |
| tmp_4_6319648_G_A | 1006 | E>K | No | 1000Genomes | |
| tmp_4_6319711_A_T | 1027 | N>Y | No | 1000Genomes | |
| tmp_4_6319724_T_C | 1031 | V>A | No | 1000Genomes | |
| tmp_4_6319752_T_G | 1040 | I>M | No | 1000Genomes | |
| ENSVATH00485170 | 1041 | M>L | No | 1000Genomes |
No associated diseases with F4JLK2
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.14 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| sucrose synthase activity | Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose. |
| sucrose-phosphate synthase activity | Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| sucrose biosynthetic process | The chemical reactions and pathways resulting in the formation of sucrose, the disaccharide fructofuranosyl-glucopyranoside. |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P31927 | SPS | Sucrose-phosphate synthase | Zea mays (Maize) | PR |
| Q43845 | SPS | Probable sucrose-phosphate synthase | Solanum tuberosum (Potato) | PR |
| Q0JGK4 | SPS1 | Probable sucrose-phosphate synthase 1 | Oryza sativa subsp japonica (Rice) | PR |
| B7F7B9 | SPS2 | Probable sucrose-phosphate synthase 2 | Oryza sativa subsp japonica (Rice) | PR |
| Q67WN8 | SPS3 | Probable sucrose-phosphate synthase 3 | Oryza sativa subsp japonica (Rice) | PR |
| Q6ZHZ1 | SPS4 | Probable sucrose-phosphate synthase 4 | Oryza sativa subsp japonica (Rice) | PR |
| Q8RY24 | SPS3 | Probable sucrose-phosphate synthase 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94BT0 | SPS1 | Sucrose-phosphate synthase 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FY54 | SPS2 | Probable sucrose-phosphate synthase 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARNDWINSY | LEAILDVGTS | KKKRFESNSK | IVQKLGDINS | KDHQEKVFGD | MNGKDHQEKV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FSPIKYFVEE | VVNSFDESDL | YKTWIKVIAT | RNTRERSNRL | ENICWRIWHL | ARKKKQIVWD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DGVRLSKRRI | EREQGRNDAE | EDLLSELSEG | EKDKNDGEKE | KSEVVTTLEP | PRDHMPRIRS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EMQIWSEDDK | SSRNLYIVLI | SMHGLVRGEN | MELGRDSDTG | GQVKYVVELA | RALANTEGVH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RVDLLTRQIS | SPEVDYSYGE | PVEMLSCPPE | GSDSCGSYII | RIPCGSRDKY | IPKESLWPHI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PEFVDGALNH | IVSIARSLGE | QVNGGKPIWP | YVIHGHYADA | GEVAAHLAGA | LNVPMVLTGH |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SLGRNKFEQL | LQQGRITRED | IDRTYKIMRR | IEAEEQSLDA | AEMVVTSTRQ | EIDAQWGLYD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GFDIKLERKL | RVRRRRGVSC | LGRYMPRMVV | IPPGMDFSYV | LTQDSQEPDG | DLKSLIGPDR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| NQIKKPVPPI | WSEIMRFFSN | PHKPTILALS | RPDHKKNVTT | LVKAFGECQP | LRELANLVLI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LGNRDDIEEM | PNSSSVVLMN | VLKLIDQYDL | YGQVAYPKHH | KQSEVPDIYR | LAAKTKGVFI |
| 610 | 620 | 630 | 640 | 650 | 660 |
| NPALVEPFGL | TLIEAAAYGL | PIVATRNGGP | VDIVKALNNG | LLVDPHDQQA | ISDALLKLVA |
| 670 | 680 | 690 | 700 | 710 | 720 |
| NKHLWAECRK | NGLKNIHRFS | WPEHCRNYLS | HVEHCRNRHP | TSSLDIMKVP | EELTSDSLRD |
| 730 | 740 | 750 | 760 | 770 | 780 |
| VDDISLRFST | EGDFTLNGEL | DAGTRQKKLV | DAISQMNSMK | GCSAAIYSPG | RRQMLFVVAV |
| 790 | 800 | 810 | 820 | 830 | 840 |
| DSYDDNGNIK | ANLNEIIKNM | IKAADLTSGK | GKIGFVLASG | SSLQEVVDIT | QKNLINLEDF |
| 850 | 860 | 870 | 880 | 890 | 900 |
| DAIVCNSGSE | IYYPWRDMMV | DADYETHVEY | KWPGESIRSV | ILRLICTEPA | AEDDITEYAS |
| 910 | 920 | 930 | 940 | 950 | 960 |
| SCSTRCYAIS | VKQGVKTRRV | DDLRQRLRMR | GLRCNIVYTH | AATRLNVIPL | CASRIQALRY |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| LSIRWGIDMS | KTVFFLGEKG | DTDYEDLLGG | LHKTIILKGV | VGSDSEKLLR | SEENFKREDA |
| 1030 | 1040 | ||||
| VPQESPNISY | VKENGGSQEI | MSTLEAYGIK |