AiPD: Autoinhibited Protein Database

Gene name	VIP2
Protein name	Protein PAF1 homolog
Names	Protein EARLY FLOWERING 7, Protein VERNALIZATION INDEPENDENCE 2
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT1G79730
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-216 (Predicted disordered autoinhibitory region) PR

1-216 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-F4HQA1-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
tmp_1_30003810_G_A	54	H>Y	No	1000Genomes
ENSVATH00150386	97	H>R	No	1000Genomes
tmp_1_30003668_G_A	101	A>V	No	1000Genomes
tmp_1_30003616_G_T	118	H>Q	No	1000Genomes
ENSVATH00150385	120	H>Y	No	1000Genomes
ENSVATH01560738	125	P>L	No	1000Genomes
ENSVATH13841198	142	R>S	No	1000Genomes
tmp_1_30003482_G_A	163	S>F	No	1000Genomes
tmp_1_30003046_C_T	256	V>M	No	1000Genomes
tmp_1_30002954_G_C	258	N>K	No	1000Genomes
tmp_1_30002938_C_T	264	A>T	No	1000Genomes
ENSVATH14495008	269	E>Q	No	1000Genomes
tmp_1_30002862_C_T	289	R>Q	No	1000Genomes
tmp_1_30002784_G_A	315	S>L	No	1000Genomes
ENSVATH13841196	365	A>V	No	1000Genomes
tmp_1_30001878_C_T	417	E>K	No	1000Genomes
ENSVATH13841187	418	S>A	No	1000Genomes
tmp_1_30001600_G_A	432	T>I	No	1000Genomes
tmp_1_30001444_A_G	449	L>S	No	1000Genomes
tmp_1_30001379_C_T	471	D>N	No	1000Genomes
tmp_1_30001120_G_A	497	P>L	No	1000Genomes
tmp_1_30000988_G_A	541	S>L	No	1000Genomes
ENSVATH05176011	555	M>L	No	1000Genomes
tmp_1_30000798_G_C	572	P>R	No	1000Genomes
tmp_1_30000753_T_A	587	Y>F	No	1000Genomes

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for F4HQA1

		Description
EC Number
Subcellular Localization	Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
Cdc73/Paf1 complex	A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
chromatin binding	Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
RNA polymerase II complex binding	Binding to an RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.

Name	Definition
flower development	The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.
histone methylation	The modification of histones by addition of methyl groups.
negative regulation of flower development	Any process that stops, prevents, or reduces the frequency, rate or extent of flower development.
transcription elongation by RNA polymerase II promoter	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins