Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for F2XG53
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-F2XG53-F1 | Predicted | AlphaFoldDB |
No variants for F2XG53
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for F2XG53 | |||||
No associated diseases with F2XG53
6 regional properties for F2XG53
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Helicase, C-terminal | 580 - 668 | IPR001650 |
| domain | Helicase Cas3, CRISPR-associated, core | 305 - 708 | IPR006474 |
| domain | CRISPR-associated Cas3-type HD domain | 9 - 236 | IPR006483 |
| domain | DEAD/DEAH box helicase domain | 294 - 493 | IPR011545 |
| domain | Helicase superfamily 1/2, ATP-binding domain | 282 - 520 | IPR014001 |
| domain | Cas3, C-terminal | 805 - 914 | IPR041372 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| deoxyribonuclease activity | Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid. |
| helicase activity | Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix. |
| metal ion binding | Binding to a metal ion. |
| nucleic acid binding | Binding to a nucleic acid. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response to virus | Reactions triggered in response to the presence of a virus that act to protect the cell or organism. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKHINDYFWA | KKTEENSRLL | WLPLTQHLED | TKNIAGLLWE | HWLSEGQKVL | IENSINVKSN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IENQGKRLAQ | FLGAVHDIGK | ATPAFQTQKG | YANSVDLDIQ | LLEKLERAGF | SGISSLQLAS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PKKSHHSIAG | QYLLSHYGVD | EDIATIIGGH | HGRPVDDLDG | LNSQKSYPSN | YYQDEKKDSL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VYQKWKSNQE | AFLNWALTET | GFNSVSQLPK | IKQPAQVILS | GLLIMSDWIA | SNEHFFPLLS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LDETDVKNKS | QRIETGFKKW | KKSNLWQPET | FVDLVTLYQE | RFGFSPRNFQ | LILSQTIEKT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TNPGIVILEA | PMGIGKTEAA | LAVSEQLSSK | KGCSGLFFGL | PTQATSNGIF | KRIEQWTENI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KGNNSDHFSI | QLVHGKAALN | TDFIELLKGN | TINMDDSENG | SIFVNEWFSG | RKTSALDDFV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VGTVDQFLMV | ALKQKHLALR | HLGFSKKVIV | IDEVHAYDAY | MSQYLLEAIR | WMGAYGVPVI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ILSATLPAQQ | REKLIKSYMA | GMGVKWRDIE | NIDQIKIDAY | PLITYNDGPD | IHQVKMFEKQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EQKNIYIHRL | PEEQLFDIVK | EGLDNGGVVG | IIVNTVRKSQ | ELARNFSDIF | GDDMVDLLHS |
| 610 | 620 | 630 | 640 | 650 | 660 |
| NFIATERIRK | EKDLLQEIGK | KAIRPPKKII | IGTQVLEQSL | DIDFDVLISD | LAPMDLLIQR |
| 670 | 680 | 690 | 700 | 710 | 720 |
| IGRLHRHKIK | RPQKHEVARF | YVLGTFEEFD | FDEGTRLVYG | DYLLARTQYF | LPDKIRLPDD |
| 730 | 740 | 750 | 760 | 770 | 780 |
| ISPLVQKVYN | SDLTITFPKP | ELHKKYLDAK | IEHDDKIKNK | ETKAKSYRIA | NPVLKKSRVR |
| 790 | 800 | 810 | 820 | 830 | 840 |
| TNSLIGWLKN | LHPNDSEEKA | YAQVRDIEDT | VEVIALKKIS | DGYGLFIENK | DISQNITDPI |
| 850 | 860 | 870 | 880 | 890 | 900 |
| IAKKVAQNTL | RLPMSLSKAY | NIDQTINELE | RYNNSHLSQW | QNSSWLKGSL | GIIFDKNNEF |
| 910 | 920 | ||||
| ILNGFKLLYD | EKYGVTIERL | DKNESV |