F2JVW9

PR
Gene name
ftsW
Protein name
Probable peptidoglycan glycosyltransferase FtsW
Names
PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase
Species
Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1)
KEGG Pathway
mme:Marme_2523
EC number
2.4.1.129: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

351-406 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for F2JVW9

Entry ID Method Resolution Chain Position Source
AF-F2JVW9-F1 Predicted AlphaFoldDB

No variants for F2JVW9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for F2JVW9

No associated diseases with F2JVW9

9 regional properties for F2JVW9

Type Name Position InterPro Accession
domain Elongation factor EFG, domain V-like 600 - 687 IPR000640
domain Translational (tr)-type GTP-binding domain 10 - 285 IPR000795
domain Translation elongation factor EFTu-like, domain 2 324 - 391 IPR004161
domain Small GTP-binding protein domain 11 - 182 IPR005225
domain Translation elongation factor EFG/EF2, domain IV 479 - 598 IPR005517
domain Elongation factor G, domain III 405 - 480 IPR009022
conserved_site Tr-type G domain, conserved site 53 - 68 IPR031157
domain EFG, domain V 603 - 680 IPR035649
domain Elongation Factor G, domain II 404 - 478 IPR041095

Functions

Description
EC Number 2.4.1.129 Hexosyltransferases
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
  • Localizes to the division septum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
peptidoglycan glycosyltransferase activity Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate.

4 GO annotations of biological process

Name Definition
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
FtsZ-dependent cytokinesis A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.
peptidoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
regulation of cell shape Any process that modulates the surface configuration of a cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKIQLRDIFE PLSANHMAKV DLWFVMSLIA ILALGIVMVA SASISVSESI HNTPYFFMGR
70 80 90 100 110 120
QILYLILGVS FGFMMLQIPT QNLQKWGILL MLLSLVLLVL VLVPGIGKTV NGSRRWINLI
130 140 150 160 170 180
VFNLQASEVA KVCMVVYVSG YLVRRAERVR ENLIGFALPL FLTSLFLIFL LMEPDFGASV
190 200 210 220 230 240
VLIGTVIALL FIGGAPVYQF IAIVIMAVLV MAGLALSESY RVKRLMNFVD PWADPFNDGY
250 260 270 280 290 300
QLSQALIAYG RGEWFGLGLG NSVQKLSYLP EAHTDFVFSI WVEEMGLLGG VVLLSLFALM
310 320 330 340 350 360
LSRIFKIGHR ALMGARPFAG YMCFGFAILI LAQVIINVGV NTGFLPTKGL TLPLISYGGS
370 380 390 400
SLIITLGSLF VVARVDIENK LASKGGESEE RKRKSDESID DGEALA