F2JTX5

PR
Gene name
rlmD
Protein name
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
Names
23S rRNA(m5U1939)-methyltransferase
Species
Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1)
KEGG Pathway
mme:Marme_1121
EC number
2.1.1.190: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-44 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for F2JTX5

Entry ID Method Resolution Chain Position Source
AF-F2JTX5-F1 Predicted AlphaFoldDB

No variants for F2JTX5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for F2JTX5

No associated diseases with F2JTX5

2 regional properties for F2JTX5

Type Name Position InterPro Accession
domain TRAM domain 10 - 72 IPR002792
active_site RNA methyltransferase TrmA, active site 366 - 396 IPR030390

Functions

Description
EC Number 2.1.1.190 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
iron ion binding Binding to an iron (Fe) ion.
RNA binding Binding to an RNA molecule or a portion thereof.
rRNA (uridine-C5-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRKRTGRRPP QKNNKFPIYT KEFLVEGLTH DAKGVARDEG KVIFIEGALP GERVEAQVVK
70 80 90 100 110 120
QGRRFDEAKT KKVLIESSSR VAPACAHFVE CGGCQFQHLI YPDQVEAKTE WLSGQFRKLA
130 140 150 160 170 180
IGDIELLSDH SEAYRRRARL SVFTKGGEHQ IGFRARSSKD IVNIANCLVL TESLQSVFVA
190 200 210 220 230 240
LKERLHESSL TSRIGHVELL EDESGSSITI RLSREISATD ESDWMVWASE VGVNLYWQRA
250 260 270 280 290 300
DESRISTARK HYYYVDGLNI QFHPQDFIQV NASMNEKMVE QAMRWLAPTK EDIVLDLFCG
310 320 330 340 350 360
SGNFSLPLAR RAGEVLGVEG LETMVEFARL NAQENDLDNV QFIAADLTKP APKVLKSKKV
370 380 390 400 410 420
TKVLLDPPRS GAFEFLETLV KFKPEQILYV SCNASTLARD AEYLIANGYV VSRVSLMEMF
430
PQTAHAEAMM LLQRK