E9DUF4

PR
Gene name
LAP1 (MAC_01252)
Protein name
Leucine aminopeptidase 1
Names
Leucyl aminopeptidase 1, LAP1
Species
Metarhizium acridum (strain CQMa 102)
KEGG Pathway
maw:MAC_01252
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

47-138 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for E9DUF4

Entry ID Method Resolution Chain Position Source
AF-E9DUF4-F1 Predicted AlphaFoldDB

No variants for E9DUF4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for E9DUF4

No associated diseases with E9DUF4

2 regional properties for E9DUF4

Type Name Position InterPro Accession
domain Peptidase M28 167 - 373 IPR007484
binding_site EF-Hand 1, calcium-binding site 201 - 213 IPR018247

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

3 GO annotations of molecular function

Name Definition
aminopeptidase activity Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain.
metal ion binding Binding to a metal ion.
metalloexopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRLSQVSVLA ACVPAAMARF VELMEANNVV LGPDEPAFLI ETAPGKTQWV TEEQKWELRR
70 80 90 100 110 120
DGQRFMDVTA TQDLGSQGLR IKESVEFPKK CVNQKEVNSL AKHLDTAPMK ANLEKLSSFH
130 140 150 160 170 180
TRYYNSDWGL KSSDWVLKKV NEIIKEAGAD KTVTAQSFPH TWKQHSVIAT IPGQTNSTII
190 200 210 220 230 240
IGAHQDSINL WLPILAAPGA DDDGSGTVTI MEVFRALLKS KDVVGGKAIN TIEFHWYSAE
250 260 270 280 290 300
EGGLLGSQAI FQQYEKQQRD VKAMLQQDMT GYIKGTLDAD LPESVGVIVD YVHAGLTKFI
310 320 330 340 350 360
KTVIEQYCAI PWVETKCGYA CSDHASASKA GYPSAFVIES SFDKSDPNIH TTSDLIEYLS
370 380 390
FDHMLQHGHM TLGFVHELGF HNFAKTVEGE SEL