Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for E8ZB61
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-E8ZB61-F1 | Predicted | AlphaFoldDB |
No variants for E8ZB61
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for E8ZB61 | |||||
No associated diseases with E8ZB61
3 regional properties for E8ZB61
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Sugar transporter, conserved site | 82 - 98 | IPR005829-1 |
| conserved_site | Sugar transporter, conserved site | 124 - 149 | IPR005829-2 |
| domain | Major facilitator superfamily domain | 28 - 439 | IPR020846 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate transport | The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLKPPVDAPI | DVKDWIDNRP | IAAYQWLILV | LCFLIVLFDG | FDVAVMGFIA | PSLMQDWGLS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RAAFGPVMSA | GMVGLAIGAL | TAGPYADRLG | RKKVLLIAVS | GFSLLSLACA | FARNPYELAV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LRLLTGIALG | AAMPNCTTLL | AEYLPTRNRS | LMITIMFTGF | NMGSGLGGFL | SAWLIPHHGW |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KSVLLAGGLL | PLALLPLLWW | LLPESARFLA | ARQAPASQIA | AALAKLGGRF | AAGTRFTVSE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PTTQHKAPAR | QLFSERYRFG | TLALWLTYFM | GLLVIYLTMG | WLPTLLRDGG | LSIERAATIT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GLFQIGGAVG | AIVVGWIMDR | RNPNRVIAIA | YALGGLCIVS | LGALSLESSL | LVVGVAAAGF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| CMSGAQTALN | AFAPGYYPTE | FRATGVSWML | GIGRFGAIFG | SLIGGAVLSL | GLGLPLLFTL |
| 430 | 440 | ||||
| LGLPAFAAAL | AILANGHARL | RATPAVTAP |