Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for E8XYF5

Entry ID Method Resolution Chain Position Source
AF-E8XYF5-F1 Predicted AlphaFoldDB

No variants for E8XYF5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for E8XYF5

No associated diseases with E8XYF5

7 regional properties for E8XYF5

Type Name Position InterPro Accession
domain Dynamin stalk domain 225 - 509 IPR000375
domain Dynamin, GTPase domain 1 - 302 IPR001401
domain Dynamin GTPase effector 639 - 730 IPR003130
conserved_site Dynamin, GTPase region, conserved site 51 - 60 IPR019762
domain GTPase effector domain 644 - 735 IPR020850
domain Dynamin-type guanine nucleotide-binding (G) domain 22 - 302 IPR030381
domain Dynamin, N-terminal 28 - 216 IPR045063

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
3'-5'-exoribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
magnesium ion binding Binding to a magnesium (Mg) ion.
single-stranded DNA 3'-5' exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFEIGINLTS SQFDKDRLQV VERARTAGLS GMLITGTSAQ ESVEAQKMAD EHPDFCWSTA
70 80 90 100 110 120
GVHPHQASHW NAQVEAGIRE LAVLPNVVAI GECGLDFNRN FSPADRQEAA FTAQLALAKE
130 140 150 160 170 180
LQLPVFLHCR DAGERFATLL KPWLSDLPGG VVHCFTGTRQ ELELYLSLGL SIGITGWVCD
190 200 210 220 230 240
ERRGLELRDM LPLIPADRLM LETDAPYLLP RDMENKPKNR RNEPAFLPHI VKQVALWRGE
250 260
DPQWLADITD DNARKLFALS ARR