E7FHP1
Gene name |
acdBI |
Protein name |
Acetate--CoA ligase [ADP-forming] I subunit beta |
Names |
ADP-forming acetyl coenzyme A synthetase I subunit beta, ACS I subunit beta |
Species |
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) |
KEGG Pathway |
pfu:PF1787 |
EC number |
6.2.1.13: Acid--thiol ligases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for E7FHP1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-E7FHP1-F1 | Predicted | AlphaFoldDB |
No variants for E7FHP1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for E7FHP1 | |||||
No associated diseases with E7FHP1
1 regional properties for E7FHP1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ATP-grasp fold | 27 - 63 | IPR011761 |
Functions
| Description | ||
|---|---|---|
| EC Number | 6.2.1.13 | Acid--thiol ligases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| acetate-CoA ligase (ADP-forming) activity | Catalysis of the reaction: ATP + acetate + CoA = ADP + phosphate + acetyl-CoA. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| metal ion binding | Binding to a metal ion. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDRVAKAREI | IEKAKAENRP | LVEPEAKEIL | KLYGIPVPEF | KVARNEEEAV | KFSGEIGYPV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VMKIVSPQII | HKSDAGGVKI | NIKNDEEARE | AFRTIMQNAR | NYKPDADLWG | VIIYRMLPLG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| REVIVGMIRD | PQFGPAVMFG | LGGIFVEILK | DVSFRVAPIT | KEDALEMIRE | IKAYPILAGA |
| 190 | 200 | 210 | 220 | 230 | |
| RGEKPVNIEA | LADIIVKVGE | LALELPEIKE | IDINPIFAYE | DSAIAVDARM | IL |