E5A0U8

PR
Gene name
ECM14 (Lema_P103750)
Protein name
Inactive metallocarboxypeptidase ECM14
Names
Species
Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-124 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for E5A0U8

Entry ID Method Resolution Chain Position Source
AF-E5A0U8-F1 Predicted AlphaFoldDB

No variants for E5A0U8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for E5A0U8

No associated diseases with E5A0U8

10 regional properties for E5A0U8

Type Name Position InterPro Accession
repeat WD40 repeat 45 - 85 IPR001680-1
repeat WD40 repeat 87 - 126 IPR001680-2
repeat WD40 repeat 131 - 170 IPR001680-3
repeat WD40 repeat 184 - 224 IPR001680-4
repeat WD40 repeat 227 - 268 IPR001680-5
repeat WD40 repeat 385 - 464 IPR001680-6
repeat WD40 repeat 489 - 529 IPR001680-7
domain Lethal giant larvae homologue 2 276 - 384 IPR013577
domain Lethal giant larvae (Lgl)-like, C-terminal domain 906 - 1026 IPR013905
domain v-SNARE, coiled-coil homology domain 1086 - 1146 IPR042855

Functions

Description
EC Number
Subcellular Localization
  • Vacuole
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
vacuole A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

1 GO annotations of molecular function

Name Definition
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRQPTFAALS LLLVAPSLVA AVPHDSTSTS TSTSTRSPSY DPDSTAAHDT TTPHTPPSPW
70 80 90 100 110 120
RRLSEAIIRR IGSLPHENHL QKSMLALATG PSSRAPGKQW VAHYGGDVVL RFKMQTADEA
130 140 150 160 170 180
RALSQAAATL FLDVWEFNED WADIRLAKDV LPSLLGLLPR SLHASYEPLM QDAALVQAIF
190 200 210 220 230 240
DTYPSSSASP SHNTNRFSPN LRPSPHHANG HPFFQDYQPL SVIDPWMSLM SSMFTTHVRK
250 260 270 280 290 300
INIGISYEGR DIPALRVGVH PTNKDEPTKP RKTVLITAGL HAREWISTST VNYLAWSVIN
310 320 330 340 350 360
AYGKDREITH LLEKFDFVFV PTLNPDGYVY TWETDRLWRK NRQPTSLRFC HGIDLDRSFP
370 380 390 400 410 420
YQWNGDQMGS NPCSESFAGD APFEGVESQR FADWARNETE SNNVEFVGLL DLHSYSQQIL
430 440 450 460 470 480
YPYSYSCHDE PPSLEDLEEL GLGLAKAIRI SRKGHTYKVT SACEGNVAFA NKEKTVLPRI
490 500 510 520 530 540
ESSGGSALDF FYHELRVKYS YQIKLRDTGN YGFLLPKEEI IPTGEEMLDA VLYLGRFMLG
550 560 570
EVGWARRRSR SRWSAPDRGT GDFDEAEQVA IEL