E2IUB0

PR
Gene name
Protein name
Cycloartenol synthase
Names
KdCAS
Species
Kalanchoe daigremontiana (Devil's backbone) (Bryophyllum daigremontianum)
KEGG Pathway
EC number
5.4.99.8: Transferring other groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

41-119 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for E2IUB0

Entry ID Method Resolution Chain Position Source
AF-E2IUB0-F1 Predicted AlphaFoldDB

No variants for E2IUB0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for E2IUB0

No associated diseases with E2IUB0

2 regional properties for E2IUB0

Type Name Position InterPro Accession
conserved_site Amidase, conserved site 146 - 177 IPR020556
domain Amidase signature domain 25 - 442 IPR023631

Functions

Description
EC Number 5.4.99.8 Transferring other groups
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
lipid droplet An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.

1 GO annotations of molecular function

Name Definition
cycloartenol synthase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol.

2 GO annotations of biological process

Name Definition
steroid biosynthetic process The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
triterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MWKLKIADAG GSQWLRSVNN HIGRQIWDFD PALGSPEELA QIEDARDNFA RHRFDKKHSA
70 80 90 100 110 120
DLLMRFQLTK ENPQSDLLPK VNIGKIEDIT EDAVTNTLRR AINFHSTTQA HDGHWPGDYG
130 140 150 160 170 180
GPLFLMPGLV ITLSITGALN AVLSKEHKKE MCRYLYNHQN EDGGWGLHIE GPSTMFGSVL
190 200 210 220 230 240
NYVTLRLLGE DVNGGDGEIE RARKWILDHG GATAITSWGK MWLSVLGVFE WCGNNPLPPE
250 260 270 280 290 300
MWLFPYYLPV HPGRMWCHCR MVYLPMSYLY GKRFVGPITP TVLSLRKELF TVPYHEIDWN
310 320 330 340 350 360
EARSLCAKED LYYPHPVVQD ILWATLHKVV EPVLLNWPGK KLREKALCSA IEHIHYEDEN
370 380 390 400 410 420
TRYICIGPVN KVLNMLCCWV EDPNSEAFKL HIPRLYDYLW IAEDGMKMQG YNGSQLWDTA
430 440 450 460 470 480
FSVQAIVATK LVEEFSSTIS KAHEFMKNSQ VLEDYPGDLS YWYRHISKGA WPFSTADHGW
490 500 510 520 530 540
PISDCTAEGL KVVLKLSQFP AELVGAPLSA KLVYNAVNVI LSLQNIDGGF ATYELTRSYS
550 560 570 580 590 600
WMELLNPAET FGDIVIDYPY VECTSAALQS LVLFKKLHPE HRKEEVELCI KKAAAFIEKI
610 620 630 640 650 660
QESDGSWYGS WAVCFTYGTW FGVLGLVAAG RNYKNSPSIR KACDFLLSKQ LASGGWGESY
670 680 690 700 710 720
LSCQNKVYTN IPGGRSHVVN TGWAMLALIG AGQAERDPVP LHRAAKFLIE SQLENGDFPQ
730 740 750 760
QEIMGVFNKN CMISYAAYRN IFPIWALGEY RCKVLNASRG QMKT