E1QUT8
Gene name |
pus10 |
Protein name |
tRNA pseudouridine synthase Pus10 |
Names |
tRNA pseudouridine 54/55 synthase, Psi54/55 synthase |
Species |
Vulcanisaeta distributa (strain DSM 14429 / JCM 11212 / NBRC 100878 / IC-017) |
KEGG Pathway |
vdi:Vdis_0543 |
EC number |
5.4.99.25: Transferring other groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for E1QUT8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-E1QUT8-F1 | Predicted | AlphaFoldDB |
No variants for E1QUT8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for E1QUT8 | |||||
No associated diseases with E1QUT8
1 regional properties for E1QUT8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | THUMP domain | 22 - 195 | IPR004114 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.4.99.25 | Transferring other groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| tRNA binding | Binding to a transfer RNA. |
| tRNA pseudouridine synthase activity | Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA pseudouridine synthesis | The intramolecular conversion of uridine to pseudouridine in a tRNA molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSIERAMDIL | RKYPLCNHCL | GRLFARLGTG | LDNEERGRAI | KDYLLMRIHE | RILNEGLSDE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LLNDVKALAV | SGHEPSIKFL | SNMGINVSPA | RCYVCGDTIF | NRLNEWVNNI | VNSLRSLGIE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FRSFRLGSRV | PLDIQNRELS | ITTEFNISSA | ESIKREINRE | LGKRVSAMLG | VSFNREEPDV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EVVIDVNTGS | VEVQIMPIYI | SARYRKVHRL | INEEGQVKWP | IDRVIQAYNA | QDVVIHTGGE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DPMGVRVLGN | GRPVILQVVK | PSKRPDVNDV | YALLKDSGYD | IVLDNLSRVR | ASAVVKMKAR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VRDYVITYRV | LAITDNSVTN | ENIKSLHDYF | RNRQVVQVFR | RGRRIRRRIS | MVYELDGRVI |
| 370 | 380 | 390 | 400 | 410 | |
| RDRLVEFLIR | CQGNLYIRGF | VHGGLGDVEP | SIAGTLGFSV | RPVEIDILNI | SD |