D9PYS9

PR
Gene name
MTBMA_c00120
Protein name
dITP/XTP pyrophosphatase
Names
Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase
Species
Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum)
KEGG Pathway
mmg:MTBMA_c00120
EC number
3.6.1.66: In phosphorus-containing anhydrides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

131-187 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for D9PYS9

Entry ID Method Resolution Chain Position Source
AF-D9PYS9-F1 Predicted AlphaFoldDB

No variants for D9PYS9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for D9PYS9

No associated diseases with D9PYS9

2 regional properties for D9PYS9

Type Name Position InterPro Accession
domain Ribosomal protein L46, N-terminal 43 - 139 IPR021757
domain Mitochondrial ribosomal protein L46 NUDIX 142 - 273 IPR033650

Functions

Description
EC Number 3.6.1.66 In phosphorus-containing anhydrides
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

6 GO annotations of molecular function

Name Definition
dITP diphosphatase activity Catalysis of the reaction: dITP + H2O = dIMP + H+ + diphosphate.
ITP diphosphatase activity Catalysis of the reaction: ITP + H2O = IMP + H+ + diphosphate.
metal ion binding Binding to a metal ion.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
ribonucleoside triphosphate phosphatase activity Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.
XTP diphosphatase activity Catalysis of the reaction: XTP + H2O = XMP + H+ + diphosphate.

2 GO annotations of biological process

Name Definition
nucleotide metabolic process The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
purine nucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKVTFITGNK HKLSEAEKIF HDTGIELEHA DLGYPELQGT LEEVARYGAE HAARIMDGPV
70 80 90 100 110 120
IVEDAGLFIR ALKWFPGPYS AYVQDTIGNR GILKLMENVE DRYAEFRSAV GFCAPKSEPE
130 140 150 160 170 180
VFLGVVKGRI GTEERGTRGF AFDPLFYPEG MDRSFGELST IEKNRFSHRS RALKKFAQWY
TENYEVI