Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for D4D9R6

Entry ID Method Resolution Chain Position Source
AF-D4D9R6-F1 Predicted AlphaFoldDB

No variants for D4D9R6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for D4D9R6

No associated diseases with D4D9R6

5 regional properties for D4D9R6

Type Name Position InterPro Accession
repeat Pumilio RNA-binding repeat 118 - 153 IPR001313-1
repeat Pumilio RNA-binding repeat 154 - 189 IPR001313-2
repeat Pumilio RNA-binding repeat 230 - 265 IPR001313-3
repeat Pumilio RNA-binding repeat 372 - 407 IPR001313-4
repeat Pumilio RNA-binding repeat 408 - 445 IPR001313-5

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPREKKKRGR RAEKSQSKRK REDEEGSDSP KRQRTTNEDN DVQAGDDYIP LVTHDTEKEQ
70 80 90 100 110 120
EQGQEDDTPF YGLLDTEEQE YFSKASQTLE LNSFEDDDDK RLFIESVYTE AKGKELKIAC
130 140 150 160 170 180
SQSCSRLMEK LIAMSTPDQV KALFEKFSGH FLHLVQHRFA SHCCECLFIR AAPIVTSEME
190 200 210 220 230 240
KPKDKKKDRK QTTETNGEDG EQDEPMNQKP AMDLFLGVVS ELEGNWGYLL TESFASHTIR
250 260 270 280 290 300
VLLLILAGEP LADHSNARVL ASRKKENVDS ITSTAQAELT IRESRQVPAE FNSTLRKMIS
310 320 330 340 350 360
DLSAGLNSTY LQALATHPIG SPVLQVILSI ELGCMGKEKV KDKSSVFRRL VPDDTLETKE
370 380 390 400 410 420
EGVNFLNSLF YDPVGSRLLE TIVRVAPGKF FKTFYKTIIR ERIGSLARNE IASYVVIKVL
430 440 450 460 470 480
ERVSREDLQS AIESILPEIP SLVQRSRLNV IKTIIDRSTV RSADTTSLAK ALESAYGEDG
490 500 510 520 530 540
LVRLKTILGV EATDKDAESV KPKAATSAQH LHGSLLAQAM LQAPGRLATM IQTSFLAAPV
550 560 570 580 590 600
EILIQIAKNS TASRALQEAL KPSKSNTQFR RQLLPQFYGQ MCDLSLDSSG SHVADALWDA
610 620 630 640 650 660
TSDLVFIKQR LAQELVDNES ALRDSFLGRA VWRNWSMDLY KRKRGEWMSR AKGLDNPRVS
670 680 690 700 710
APTADSSAEP AKSKLDLARA RYAARAEQQE KPDSREQGPR GKKQALSAPS GLLKAQ