D4AZ71

PR
Gene name
CPYA (ARB_01491)
Protein name
Carboxypeptidase Y homolog A
Names
Species
Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes)
KEGG Pathway
abe:ARB_01491
EC number
3.4.16.5: Serine-type carboxypeptidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-141 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for D4AZ71

Entry ID Method Resolution Chain Position Source
AF-D4AZ71-F1 Predicted AlphaFoldDB

No variants for D4AZ71

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for D4AZ71

No associated diseases with D4AZ71

5 regional properties for D4AZ71

Type Name Position InterPro Accession
domain Helicase-like, DEXD box c2 type 9 - 314 IPR006554
domain ATP-dependent helicase, C-terminal 556 - 738 IPR006555
domain RAD3-like helicase, DEAD 124 - 286 IPR010614
domain Helicase superfamily 1/2, ATP-binding domain 13 - 320 IPR014001
domain Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type 7 - 318 IPR014013

Functions

Description
EC Number 3.4.16.5 Serine-type carboxypeptidases
Subcellular Localization
  • Vacuole
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
vacuole A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

1 GO annotations of molecular function

Name Definition
serine-type carboxypeptidase activity Catalysis of the hydrolysis of a single C-terminal amino acid residue from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKFLTTGLLA TAALAAAQEQ QVLQAEDGHG QAPQRDASIF DETLQKFQSS LEDGISHFWS
70 80 90 100 110 120
EMKTNFKDYL PLISLPKKHT RRPDSEWDHV VRGADIESVW VQGADGEKRR EIDGKLHNYD
130 140 150 160 170 180
LRVKAVDPSK LGVDPGVKQY SGYLDDNDAD KHLFYWFFES RNDPKNDPVV LWLNGGPGCS
190 200 210 220 230 240
SLTGLFLELG PATIDKNLKV VSNPYSWNSN ASVIFLDQPV NVGFSYSGSS VSDTVAAGKD
250 260 270 280 290 300
VYALLTLFFK QFPEYASQDF HISGESYAGH YIPVFAAEIL SHKNTNINLK SALIGNGLTD
310 320 330 340 350 360
PLTQYPQYRP MACGEGGYPA VLDQGTCRSM DNSLERCLSL IETCYSSESA WVCVPAAMYC
370 380 390 400 410 420
NSAILAPYQQ TGMNPYDVRT KCEDMASLCY PQLNAITEWL NQESVMQALG VEVQSYESCN
430 440 450 460 470 480
SGINRDFLFH GDWMKPYHRL VPSVLEKIPV LIYAGDADFI CNWLGNLAWT DALEWPGHKK
490 500 510 520 530 540
FAEAKLEDLK IVNNKDKGKK IGQVKSSGNF TFMRIFGAGH MVPLNQPEAS LEFFNRWLGG
EWH