D4AMV1

PR
Gene name
ARB_05554
Protein name
Vacuolar membrane protease
Names
FXNA-related family protease 1
Species
Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes)
KEGG Pathway
abe:ARB_05554
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

13-87 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for D4AMV1

Entry ID Method Resolution Chain Position Source
AF-D4AMV1-F1 Predicted AlphaFoldDB

No variants for D4AMV1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for D4AMV1

No associated diseases with D4AMV1

1 regional properties for D4AMV1

Type Name Position InterPro Accession
domain Peptidase M28 161 - 336 IPR007484

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
metalloexopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVSSRRGFNP IAFTPWPVTI LSSLVYLALI IPIIVVHHLV PPAPKESPAG VDLEEAWHDL
70 80 90 100 110 120
QHLTRQYHPY NSHSNDEVHQ WLLKRIHAIS ATSARSESQS GPEVFVFDDN QTNLTFSSAG
130 140 150 160 170 180
VAATAITGVY FESRNIVVYI RGTEDEPGEW WKSPDGEPSG KGGVLVNAHY DSVSTGYGAT
190 200 210 220 230 240
DNGVGVITTL QLLKYFTTPG HYPRKGLVLL FNNGEEDFLN GAYAYSQHPM SKFTHTFLNL
250 260 270 280 290 300
EGAGAGGRAV LFRSTDTEVT RFYGKSEHPF GTVLARDAFK LKFIRSETDY HVFDGVFGMR
310 320 330 340 350 360
GLDVAFMEPR SRYHTDQDDA RHTSIDSVWH MLSAAITTTE GLVSYTGDAF DGDSGDGGKL
370 380 390 400 410 420
NNGIGTLGVW FDFFGSSFAV FQLNTLFGHS VALLVVAPLL LIITSVALFA VDKMYMFSMY
430 440 450 460 470 480
TYISESGGQV SLYGLRGMFR FPLILGISTA LTIALAFLIM KVNPFIIYSS PYAVWSMMLS
490 500 510 520 530 540
TCMFFAWFIS CVADFARPSA LHRAYSFSWM FGIMWVFLVI ATVYQKQHGI ASSYFIVFYF
550 560 570 580 590 600
AGVAVATWIS YLELFGLPKT QDYARRQGRL SDRTPSSDSH FLAPSADELP SSSSAAGRDF
610 620 630 640 650 660
NPEDVEDEEP TESTSLLRGQ QRTTFANYAS ARGSQESNIS NQGNNSLHPK DHRLEQKWSI
670 680 690 700 710 720
YLMSSAWILQ FLLVAPIVII LLGQLGLFLT SATYQIGADG GSQLVIYIGI AVLSVLILLP
730 740 750 760 770 780
LFPFIHRFTY HIPTFLLFIL IGTLVYNLTA FPFSHSNRLK LAFVQEMDLA TGNNQASLVG
790 800 810 820 830 840
VEPYIHDAVH AIPSVQDGKI SCTSHGYGGR TKCSWPGLKP KVAEGPYKDW VSYNISKTKD
850 860 870 880 890 900
DKITRFEVSG KNTRACKLLF DSPIADFHVQ GSVVDKRLPH TGPKGVSEIR LWSRNWENTW
910 920 930 940 950 960
TVDVEWTKKN SERTGKVMCL WSDDNDLHVI PELDLARKFA PWWVAITKLR DGLVEGSYSF
KL