D2Z028

PR
Gene name
dcsE
Protein name
L-serine/homoserine O-acetyltransferase
Names
Homoserine O-trans-acetylase
Species
Streptomyces lavendulae
KEGG Pathway
ag:BAI70379
EC number
2.3.1.30: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

66-141 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for D2Z028

Entry ID Method Resolution Chain Position Source
3VVL X-ray 181 A A/B 1-374 PDB
3VVM X-ray 170 A A/B 1-374 PDB
AF-D2Z028-F1 Predicted AlphaFoldDB

No variants for D2Z028

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for D2Z028

No associated diseases with D2Z028

1 regional properties for D2Z028

Type Name Position InterPro Accession
domain Alpha/beta hydrolase fold-1 46 - 357 IPR000073

Functions

Description
EC Number 2.3.1.30 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
homoserine O-acetyltransferase activity Catalysis of the reaction: L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA.
O-succinyltransferase activity Catalysis of the transfer of a succinyl group to an oxygen atom on the acceptor molecule.
serine O-acetyltransferase activity Catalysis of the reaction: L-serine + acetyl-CoA = O-acetyl-L-serine + CoA.

1 GO annotations of biological process

Name Definition
cysteine biosynthetic process from serine The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MREFIPPASR FIELPDGFAM RRGGALYGAR IAYETFGSLN AARDNAVLVL TGLSPDAHAA
70 80 90 100 110 120
SRPDDPTPGW WEAMVGPGKP VDTDLWHVIC VNSLGSCKGS TGPASTDPRT GEPYRLSFPE
130 140 150 160 170 180
LSIEDIADAA AHTVRALGIS RLACVVGASM GGMSALALLA RHPELARTHI SLSGAVHALP
190 200 210 220 230 240
FSIAVRSLQR EAIRSDPGWL QGHYDEGEGP RRGMLTARKL GMMTYRSAQE WDCRFGRTRI
250 260 270 280 290 300
GERRRADQGR FGPEFEVESY LDFHAQRFAD RFDPNSYLYL SHAMDQFDLG DGGGGGGGAP
310 320 330 340 350 360
GALSRMRVER ALVMGARTDI LFPLSQQQEI ADGLSAGGAD VSFLPVDTPA GHDAFLVDIE
370
RFGPPVAKFL AIVA