D2V9W6

PR
Gene name
NAEGRDRAFT_36099
Protein name
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial
Names
Glu-AdT subunit B
Species
Naegleria gruberi (Amoeba)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

465-514 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for D2V9W6

Entry ID Method Resolution Chain Position Source
AF-D2V9W6-F1 Predicted AlphaFoldDB

No variants for D2V9W6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for D2V9W6

No associated diseases with D2V9W6

3 regional properties for D2V9W6

Type Name Position InterPro Accession
domain Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic 23 - 312 IPR006075
conserved_site Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site 164 - 178 IPR017958
domain Asn/Gln amidotransferase 352 - 506 IPR018027

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
glutamyl-tRNA(Gln) amidotransferase complex A protein complex that possesses glutamyl-tRNA(Gln) amidotransferase activity, and therefore creates Gln-tRNA by amidating Glu-tRNA; usually composed of 3 subunits: A, B, and C. Note that the C subunit may not be required in all organisms.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP.

2 GO annotations of biological process

Name Definition
glutaminyl-tRNAGln biosynthesis via transamidation A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase.
mitochondrial translation The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHTNKKYLHT SGDESVLKGY KPVIGLEIHA QIKSKSKLFS TSSTEFTNSM PNVNVTLFDA
70 80 90 100 110 120
SFPGTLPSLN EYCIRQAVKT GLAVGGKINL YSQFDRKHYF YPDLPLGYQI TQQFYPLVSE
130 140 150 160 170 180
GKLRIDIPQG DGTYKPKYIR IARIQVEQDS GKSVHDLDNT LIDLNRAGNP LMEIITYPDL
190 200 210 220 230 240
NSSLEAELFV KKLQFMLRHI GTCDGNMEEG SLRCDVNVSV YNASAGDHPL SGTRCEVKNI
250 260 270 280 290 300
SSANNIPRAI DFEIKRHIEL LTNGQKIEQQ TRTFDAKKGE TLLLRSKENI PDYKFFPDPD
310 320 330 340 350 360
LPYVELTEDY VESVKTTIPS LPDDIVEKLT SEPYNLNFYD ANILLTNNGG VEFFETILHD
370 380 390 400 410 420
SRWSSKLNPK LVANWIASEL MGLLNASEIT LSDSPVSYIQ IGSIVEAIQH EDISGKMAKK
430 440 450 460 470 480
IIKIMFDEKS GEMALDIAEK NGWRQITDKN VIGELCDKII AEHPTEVGNL RNGKENVFQF
490 500 510
LVAQVIKLSK GNASPSLVNQ ILREKATNKP TTTD