D1ZV85

PR
Gene name
SMAC_04453
Protein name
Vacuolar membrane protease
Names
FXNA-related family protease 1
Species
Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)
KEGG Pathway
smp:SMAC_04453
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

543-628 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for D1ZV85

Entry ID Method Resolution Chain Position Source
AF-D1ZV85-F1 Predicted AlphaFoldDB

No variants for D1ZV85

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for D1ZV85

No associated diseases with D1ZV85

1 regional properties for D1ZV85

Type Name Position InterPro Accession
domain Peptidase M28 176 - 352 IPR007484

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
metalloexopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MINPISFRPG PVTFWTTLIY LALLIPIVII NEEPPAAPKT AEPFKGVNLT EAWLDLTTIT
70 80 90 100 110 120
RAYHPYNSKF NEEVRRYLLE KVESILEENG ATWVFDDQMA AAAKDGKSAA VTVFDDNVSN
130 140 150 160 170 180
STFVMGKSNG TTFTRTESIN NAAYFEGTNI LVYIRGKEDD DGDWWEADYV HGMRRNAKGL
190 200 210 220 230 240
TLVNAHYDSV STGFGATDDG MGVVTCLQVL KYFTTPGNQP QRGIVVMLNN GEEDWLYGAR
250 260 270 280 290 300
ALGQHKLNPF IHTFLNVEGA GAGGRAIVFR ATDREVMAAY ARTSHPFGTV IASDAFGMGF
310 320 330 340 350 360
ISSGTDYSVL VDAYGQRGID LAFFKPRARY HTNQDDTRHA SKESLWHILS ASIHTTKQLS
370 380 390 400 410 420
GDTGNTFIGQ RPDKAHGKVA NGRPSNGVWF DLFGKSFVLF GLRGMFAWSL TLLIATPLIL
430 440 450 460 470 480
VGITWLLRNL DKDYFFTSTV KTKEHPEYEA VPIGGWKGFF RWAMMVSIFY FSFWMIMRGA
490 500 510 520 530 540
NFVRPSALHR GYANLWLFVF GWIVLVAVTA LEDRRRIAAG YIFVFLESAI FLSCLISFVE
550 560 570 580 590 600
LLALPRKSAY ALQVQEDYDG HDHSGYQGYR DSTDGLSSGA RAESSASAGS PSSPTVAQEP
610 620 630 640 650 660
SKPTAPAGTT NGLSTAPSVA AHSSQPQPAP ATPTPGRSTS APIPSTTPRD EDESEDDDDE
670 680 690 700 710 720
ATERTPLVGG NGTNDRGRTT FATTYRRSIT ALVHGARKME EDGEPYEHEQ DWSGHLPSWA
730 740 750 760 770 780
WFFQFLLLGP FMIILAAQTG LMLTDAVYQT GSDGSKLFTP YLMIFFFTLL LILPLTPFIH
790 800 810 820 830 840
RVTHHIPVFL LVVFIVTLTY NLIAFPFSAN NRYKAFFGQY IDVATGENKV CYTGIEEYVR
850 860 870 880 890 900
PIIAELPSAS GRDVTCGKSL RRGSTIATCC FDGSAVPPKL GSEDLDGLPQ DNYADIITVN
910 920 930 940 950 960
ATRSHKKGDS SRTTARIEIT ADNTKSCFLQ FKKPVSALTI ESGSGWDDRF GQYPEDGVGL
970 980 990 1000 1010 1020
VRLWHREFDK TWVVNAEWKG SETRKGDDEN DGTVICMWSD ANTPGTIPAL DEALQFVPSW
1030
AAVTKFSEGL VEGRKAFKIV