D0ZSY8

PR
Gene name
rseA (STM14_3233)
Protein name
Anti-sigma-E factor RseA
Names
Regulator of SigE, Sigma-E anti-sigma factor RseA, Sigma-E factor negative regulatory protein
Species
Salmonella typhimurium (strain 14028s / SGSC 2262)
KEGG Pathway
seo:STM14_3233
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

42-216 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for D0ZSY8

Entry ID Method Resolution Chain Position Source
AF-D0ZSY8-F1 Predicted AlphaFoldDB

No variants for D0ZSY8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for D0ZSY8

No associated diseases with D0ZSY8

2 regional properties for D0ZSY8

Type Name Position InterPro Accession
domain Anti sigma-E protein RseA, N-terminal 1 - 87 IPR005572
domain Anti sigma-E protein RseA, C-terminal 132 - 186 IPR005573

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
sigma factor antagonist activity The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity.

1 GO annotations of biological process

Name Definition
cellular stress response to acid chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQKEKLSALM DGETLDSELL KALTHDPEMQ KTWESYHLIR DSMRGDTPDV LHFDISARVM
70 80 90 100 110 120
AAIENEPVRQ VSPLIPEAQP APQQWQKMPF WKKVRPWAAQ LTQMGVAACV SLAVIVGVQH
130 140 150 160 170 180
YNGQSETSQQ PETPVFNTLP MMGKASPVSL GVPSEAAPVG SQQQQVQEQR RRINAMLQDY
190 200 210
ELQRRLHSEQ LQFEQAQTQQ AAVQVPGIQT LGTQSQ