Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for C8Z3N7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-C8Z3N7-F1 | Predicted | AlphaFoldDB |
No variants for C8Z3N7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for C8Z3N7 | |||||
No associated diseases with C8Z3N7
1 regional properties for C8Z3N7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Sec7 domain | 48 - 266 | IPR000904 |
Functions
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cellular bud neck | The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding. |
| cellular bud tip | The end of a cellular bud distal to the site of attachment to the mother cell. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| guanyl-nucleotide exchange factor activity | Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular localization | A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. |
| regulation of ARF protein signal transduction | Any process that modulates the frequency, rate or extent of ARF protein signal transduction. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MCASLNEVKK | NDTYGVSQKG | YNDNFSESEG | VLHGSKSMPT | SMKNMLQSPT | MVNMCDILQN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KEAANDEKPV | IPTTDTATAG | TGTEDISSTQ | SEETDQNSHL | IASEILEGTF | KDVSYKEYAN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FLGNDNNNQV | LTEFVKLLSP | LPSSLLETLF | NLSKSIYFIA | EAQNIDRILE | CLSIEWIACH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PNTHWKSGYK | SCHIVLFSLL | ILNSDLHNNF | QVDHKKIKFS | MVAFINNTLR | ALREENEYEE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LKIYSREHLI | IEELSEYYKT | LNETPLPLCT | ESRTSINISD | NQSSLKRFST | LGSREFSTSN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LRSVNSNSTT | LYSRDGQVSV | REMSAKSNKN | FHNNHPMDAL | YLKESFDDGL | ITENGSSWFM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DDLILISKKS | LPRKYSKRDK | DQVAAPKMTS | KRNKSFFGWL | KPSKTTTLIE | HTSRRTSLSY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LNKDSEWERV | KIQVKEGRIF | IFKIKPDVKD | IIQSSETDSA | TIDYFKDISS | SYFAYSLLEA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EAHVVQDNII | IGSGAMKSNV | CNKNTKRKSG | NFTVSFPENI | NGPKLVLEFQ | TRSVEEAHKF |
| 550 | 560 | 570 | 580 | 590 | 600 |
| MDCINFWAGR | ISPVPLTQFE | AVSNAEYGWS | DKILTEHASL | NLKNIVVSEW | KPLLGLELLY |
| 610 | 620 | 630 | 640 | 650 | 660 |
| EDAKDVEMVE | LKERLKELMN | FTRQLGIWID | KHNEIKDKLV | EIWSFDDNYF | EAVMNNWNSR |
| 670 | 680 | ||||
| YLYMNNQYKK | RLSYLKALQK | AMGSVQF |