C8WJZ5

PR
Gene name
phnPP
Protein name
Phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase
Names
Cyclic phosphate dihydrolase, cPDH
Species
Eggerthella lenta (strain ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 / KCTC 3265 / NCTC 11813 / VPI 0255 / 1899 B) (Eubacterium lentum)
KEGG Pathway
ele:Elen_0235
EC number
3.1.4.57: Phosphoric diester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-51 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C8WJZ5

Entry ID Method Resolution Chain Position Source
AF-C8WJZ5-F1 Predicted AlphaFoldDB

No variants for C8WJZ5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C8WJZ5

No associated diseases with C8WJZ5

2 regional properties for C8WJZ5

Type Name Position InterPro Accession
domain Polymerase/histidinol phosphatase, N-terminal 3 - 68 IPR003141
domain PHP domain 4 - 68 IPR004013

Functions

Description
EC Number 3.1.4.57 Phosphoric diester hydrolases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
5-phospho-alpha-D-ribose 1,2-cyclic phosphate 1-phosphohydrolase activity Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> D-ribofuranose 2,5-bisphosphate + H+.
D-ribose 2,5-bisphosphate 2-phosphohydrolase activity Catalysis of the reaction: H2O + D-ribofuranose 2,5-bisphosphate <=> hydrogenphosphate + D-ribofuranose 5-phosphate.
metal ion binding Binding to a metal ion.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIEDLHVHST MSDGSDTFEQ VLEQAAQRGV ERLAFTNHDT TAGLTAAREL GERLGVQVVG
70 80 90 100 110 120
GIEVSAYDFE RGRKVHILGL GVEEGAPALA ALCGSTLERR HANSLWQLDR LVEAGYEVDV
130 140 150 160 170 180
ERALELGRAS TCLYKQHLMA ALTSEPYPSA AYRTLYRSLF KNGGICDRDI DYVDARDAVR
190 200 210 220 230 240
VVVEDGGLAV LAHPGQLDSY DLLPDLVECG LGGIERFHPD HTLADHARCA ELAVRYRLVC
250 260
TGGSDYHGKF GRVPHVGFRV PA