C7EXL6
Gene name |
hepC |
Protein name |
Heparin-sulfate lyase |
Names |
Heparin-sulfate eliminase, Heparinase III, HepIII, Heparitin-sulfate lyase |
Species |
Bacteroides stercoris |
KEGG Pathway |
|
EC number |
4.2.2.8: Acting on polysaccharides |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for C7EXL6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-C7EXL6-F1 | Predicted | AlphaFoldDB |
No variants for C7EXL6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for C7EXL6 | |||||
No associated diseases with C7EXL6
1 regional properties for C7EXL6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Heparin-sulfate lyase, N-terminal | 29 - 383 | IPR031680 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.2.2.8 | Acting on polysaccharides |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| periplasmic space | The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria). |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| heparin-sulfate lyase activity | Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNKTFKYIVL | LALACFVGKA | NAQELKTEVF | SLLNLDYPGL | EKVKALHQEG | KDADAAKALL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DYYRARTNVK | TPDINLKKVT | IGKDEQKMAD | EALQHTFFAH | KGYQPSFNYG | EDIDWRYWPV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KDNELRWQLH | RHKWFTPMGK | AYRVSGDEKY | AVEWTKQYID | WIKKNPLVKV | DKKEYEMTGD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NQLKGDVENA | RFAWRPLEVS | NRLQDQTSQF | QLFLPSPSFT | PEFLTEFLVN | YHKHAIHILG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IYSAQGNHLL | FEAQRMIYAG | AFFPEFKEAA | AWRKSGIDIM | NREINVQVYN | DGGQFELDPH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YHLAAINIFC | KALNIADLYG | FRNEFPQEYL | DTIEKMIVFY | ANVSFPDYTN | PCFSDAKLTN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KKEMLKNYRN | WSKMFPKNQF | IKYLATDGKE | GALPEYLSKG | FLKSGFFVFR | NSWGTDATQM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VVKAGPKAFW | HCQPDNGTFE | LWFNGKNLFP | DSGSYVYAGE | GEVMEQRNWH | RQTCVHNTVT |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LNNKNLDQTE | SVTKLWQPEG | NVQILVTENP | SYKNLKHRRS | VFFVDNSYFV | IVDEMVGSQK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| GSINLHYQMP | KGEIANSRED | MTFVTQFEEG | SNMKLQCFGP | EGMTMKKEPG | WCSTAYRKRY |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KRMNVSFNVK | KDSEDAVRYI | TVICPIKNSA | DAPKLSAKFK | NKTFNENGLE | VEVKVNGKKQ |
| SLNYKL |