C6E559

PR
Gene name
GM21_1532
Protein name
dTTP/UTP pyrophosphatase
Names
dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase
Species
Geobacter sp (strain M21)
KEGG Pathway
gem:GM21_1532
EC number
3.6.1.9: In phosphorus-containing anhydrides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-74 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C6E559

Entry ID Method Resolution Chain Position Source
AF-C6E559-F1 Predicted AlphaFoldDB

No variants for C6E559

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C6E559

No associated diseases with C6E559

4 regional properties for C6E559

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) 223 - 400 IPR002314
domain Aminoacyl-tRNA synthetase, class II 172 - 410 IPR006195
domain Serine-tRNA synthetase, type1, N-terminal 1 - 108 IPR015866
domain Serine-tRNA ligase catalytic core domain 120 - 417 IPR033729

Functions

Description
EC Number 3.6.1.9 In phosphorus-containing anhydrides
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
dTTP diphosphatase activity Catalysis of the reaction: dTTP + H2O = dTMP + H+ + diphosphate.
UTP diphosphatase activity Catalysis of the reaction: UTP + H2O = UMP + H+ + diphosphate.

1 GO annotations of biological process

Name Definition
nucleotide metabolic process The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKNSSIVLAS ASPRRSELLE SAGIQFRVVP ADINEEPLPG EEPVDHVQRL AEGKARAAAE
70 80 90 100 110 120
LAEGRFFLGA DTIVLCDGEI MGKPKDAVDA ERMLKKLSGV PHEVVTGFAI YDRERKGAVV
130 140 150 160 170 180
EAVRTKVFFK HLRDEEIRDY VATGCPFDKA GAYAIQGGAA HMVRKIEGSY TNVVGLPLCE
190
VVDALRVIGA LGN