C6E0B4

PR
Gene name
glyS
Protein name
Glycine--tRNA ligase beta subunit
Names
Glycyl-tRNA synthetase beta subunit, GlyRS
Species
Geobacter sp (strain M21)
KEGG Pathway
gem:GM21_0656
EC number
6.1.1.14: Ligases forming aminoacyl-tRNA and related compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

40-109 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C6E0B4

Entry ID Method Resolution Chain Position Source
AF-C6E0B4-F1 Predicted AlphaFoldDB

No variants for C6E0B4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C6E0B4

No associated diseases with C6E0B4

3 regional properties for C6E0B4

Type Name Position InterPro Accession
domain Guanylate kinase-like domain 12 - 191 IPR008144
domain Guanylate kinase/L-type calcium channel beta subunit 11 - 194 IPR008145
conserved_site Guanylate kinase, conserved site 46 - 63 IPR020590

Functions

Description
EC Number 6.1.1.14 Ligases forming aminoacyl-tRNA and related compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
arginine-tRNA ligase activity Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
glycine-tRNA ligase activity Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).

2 GO annotations of biological process

Name Definition
arginyl-tRNA aminoacylation The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
glycyl-tRNA aminoacylation The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKDLFLEIG CEEIPAGFVP KAMADMELLI KKEFDSARIE YGEIVTLGTP RRLVLAVKGV
70 80 90 100 110 120
AERQPDAELT AMGPAKSHAY DADGNPTKAA QGFARGQGID VSQLKLVTTE KGEYLAAVKS
130 140 150 160 170 180
EIGRETAELL PEMLPRLIGN IPFKKSMRWA DFDVRFARPI HWIAALFDGK VVPFSFGNID
190 200 210 220 230 240
SGSASRGHRF MANTPFPVRD LAHYLEECER HFVIPDPNKR KEIIRAEIER VAKQAKGNVL
250 260 270 280 290 300
PDEALLEQVS YLVEYPSAVH GTFSPDFLVV PREVLITSMR EHQRYFSLVD DEGKLLPGFI
310 320 330 340 350 360
TINNTITEDP QVVVKGNERV LRARLSDARF FFDEDHKVRL ETRVESLKSV VYQAKLGTSY
370 380 390 400 410 420
EKMERFRELG KRLAQRLNPS VIKQVERAAT LCKADLVSGM VGEFPEVQGI MGREYALHDG
430 440 450 460 470 480
EEPAVANAIA EHYLPTQAGG ELPASDIGAF VSLADKMDTI CGCFCVGLIP TGSADPYALR
490 500 510 520 530 540
RSALGIINII LEKGYREPLS EFVKASLDLL AAKATRPLAE VQKDVLDFFR GRFVNLMADR
550 560 570 580 590 600
FPSDAVEAVA SVSFDDLVEA AAKIEALAGF RNRDDFGPLA VAFKRVCNIV KDGVDTPVSA
610 620 630 640 650 660
ELFQDAAEGE LHQALTQVSG KVADALKKAD YLAALTEIAT LKPAVDLFFE KVMVMADDER
670 680
VRQNRLALLT GIARLFASLA DFSRLSP