Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for C6DKK3

Entry ID Method Resolution Chain Position Source
AF-C6DKK3-F1 Predicted AlphaFoldDB

No variants for C6DKK3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C6DKK3

No associated diseases with C6DKK3

7 regional properties for C6DKK3

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 398 - 567 IPR000795
domain Small GTP-binding protein domain 401 - 557 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 323 - 373 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 58 - 95 IPR013575
domain Translation initiation factor IF- 2, domain 3 674 - 788 IPR023115
domain Translation initiation factor IF-2, domain II 574 - 667 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDVTVKSLA AEIQTPVDRL IQQFADAGMT KSASDAVTQH EKETLLAHLN RDRGNAQGKL
70 80 90 100 110 120
TLQRKTRSTL NVPSTGGKSK SVQIEVRKTR TYVKRDPIDA QQAEEEEQAR REAEEQAQRA
130 140 150 160 170 180
AEEQAKREAE LREAAEKAKR AADEQAKREA AEKAKRDVAE KEKVTNQQNE NMTKPAQAEK
190 200 210 220 230 240
AKREAEAAEL KRKAEEAARL KVEEEARRIA EEARRMAEEN AGRWEAESAK PEESADYHVT
250 260 270 280 290 300
TSHHAREAED ENDRQVEGER RSRSRAGKVT KQKKGNRQSE SKADREEARA VTRGGKGKRK
310 320 330 340 350 360
PSSLQQSFNK PVQAVNRDVV IGETVTVAEL ANKMAVKGSQ VIKVMMKLGA MATINQVIDQ
370 380 390 400 410 420
ETAQLVAEEM GHKVILRREN ELEEAVMSDR DTGVAAEARA PVVTIMGHVD HGKTSLLDYI
430 440 450 460 470 480
RSTKVAAGEA GGITQHIGAY HVETDNGMIT FLDTPGHAAF TAMRARGAQA TDIVVLVVAA
490 500 510 520 530 540
DDGVMPQTIE AIQHAKAAQV PVVVAVNKID KPEADPDRVK TELSQYGVMP EEWGGESQFV
550 560 570 580 590 600
HVSAKAGTGI DELLDAILLQ AEVLELKAVR SGMANGVVIE SFLDKGRGPV ATVLVREGTL
610 620 630 640 650 660
NKGDIVLCGF EYGRVRAMRD ELGREITSAG PSIPVEILGM SGVPAAGDEA TVVRDEKKAR
670 680 690 700 710 720
EVALYRQGKF REVKLARQQK SKLENMFANM TEGEVSELNI VLKSDVQGSC EAISDSLQKL
730 740 750 760 770 780
STDEVKVKIV GSGVGGITET DATLAAASNA IILGFNVRAD ASARRIVESE SLDLRYYSVI
790 800 810 820 830 840
YDLLDEVKQA MSGMLAPEYK QEIIGLAEVR DVFKSPKFGA IAGCMVTEGI VKRHNKIRVL
850 860 870 880 890
RDNVVIYEGE LESLRRFKDD VNEVRNGMEC GIGVKNYNDV RPGDMIEVFE TIEIKRTIA