C6DGY3

PR
Gene name
clsA
Protein name
Cardiolipin synthase A
Names
CL synthase
Species
Pectobacterium carotovorum subsp carotovorum (strain PC1)
KEGG Pathway
pct:PC1_1991
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

33-143 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C6DGY3

Entry ID Method Resolution Chain Position Source
AF-C6DGY3-F1 Predicted AlphaFoldDB

No variants for C6DGY3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C6DGY3

No associated diseases with C6DGY3

5 regional properties for C6DGY3

Type Name Position InterPro Accession
domain Phospholipase D/Transphosphatidylase 219 - 246 IPR001736-1
domain Phospholipase D/Transphosphatidylase 399 - 426 IPR001736-2
domain Phospholipase D-like domain 135 - 247 IPR025202-1
domain Phospholipase D-like domain 331 - 442 IPR025202-2
domain Cardiolipin synthase N-terminal 23 - 59 IPR027379

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
cardiolipin synthase activity Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol.

1 GO annotations of biological process

Name Definition
cardiolipin biosynthetic process The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSTFYTVISW LLVFGYWLLI AGVTLRILMK RRAVPSAMAW LLVIYILPLV GIVAYLSFGE
70 80 90 100 110 120
LHLGKRRAER ASKMWPSTAK WLRELKEYRR IFATENSEVA SALFQLCERR QGVGGVKGNQ
130 140 150 160 170 180
LQLMTTFDDT IKALLRDIEL ARSNIEMVFY IWQPGGLVEQ VSSSLIAAAR RGVHCRILLD
190 200 210 220 230 240
SAGSVQFFRQ HHPELMRTAG IEVVEALKVN LFRAFLRRMD LRQHRKIILI DNRIAYTGSM
250 260 270 280 290 300
NMVDPRFFKQ DAGVGQWIDL MARIEGPVAT TLGIIYCCDW EMETGKRLLP PPPDVNVMPF
310 320 330 340 350 360
EQESGHTIQV IASGPGYPEE MIHQALLTSV YSARKQLIMT TPYFVPSDDL LHAICTAAQR
370 380 390 400 410 420
GVDVSIIVPH KNDSVLVGWA SRAFFTELLA AGVKIYQFKD GLLHTKSVLV DGQLSLVGTV
430 440 450 460 470 480
NLDMRSLWLN FEITLVIDDA GFGSDLACVQ EDYIARSRLL NATQWQNRPY WQRIVERLFY
FFSPLL