C6BTR8

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Maridesulfovibrio salexigens (strain ATCC 14822 / DSM 2638 / NCIMB 8403 / VKM B-1763) (Desulfovibrio salexigens)
KEGG Pathway
dsa:Desal_1786
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C6BTR8

Entry ID Method Resolution Chain Position Source
AF-C6BTR8-F1 Predicted AlphaFoldDB

No variants for C6BTR8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C6BTR8

No associated diseases with C6BTR8

3 regional properties for C6BTR8

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 289 - 298 IPR020557
domain Fumarate lyase, N-terminal 20 - 314 IPR022761
domain Argininosuccinate lyase, C-terminal 377 - 444 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADNKLWGGR FAAKTAQSVE DYTESVSYDQ NLYREDISGS QAHAKMLAEQ GVLTAEEAEI
70 80 90 100 110 120
LVKGLDQVLE EIESGKFEWK KEMEDLHMNI ESRLTEIVGP VGGKLHTGRS RNDQVATDFR
130 140 150 160 170 180
LHVLRSLEAW KTALEKLIAS FTAKADANRE VLLPGYTHLQ PAQPVSLAHH MLAYAWMFKR
190 200 210 220 230 240
DHSRVVDCIN RANVCPLGAA ALAGTTYPLK PATSAKYLGM EDTFRNSLDA VSDRDFVMEA
250 260 270 280 290 300
MFTGSLIMTH LSRICEELII WANPCFGFIK LPDEFSTGSS IMPQKKNPDV CELMRGKTGR
310 320 330 340 350 360
VYGDLFSLMT TCKGLPLAYN RDMQEDKEPF FDCDKTVHAS VVIMADMMDA MGFNPANMES
370 380 390 400 410 420
ALKKGFLNAT ELADYLVGKG IPFREAHHIT GSAVAKAEAE SRGLEDMSLE ELKTFSDKIE
430 440 450
EDVFEVLSYE AAVRRRVSPG STGPESVDSQ IAELKAWLKK