C6A5A3
Gene name |
taw3 |
Protein name |
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase |
Names |
tRNA wyosine derivatives biosynthesis protein Taw3 |
Species |
Thermococcus sibiricus (strain DSM 12597 / MM 739) |
KEGG Pathway |
tsi:TSIB_1747 |
EC number |
2.1.1.282: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for C6A5A3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-C6A5A3-F1 | Predicted | AlphaFoldDB |
No variants for C6A5A3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for C6A5A3 | |||||
No associated diseases with C6A5A3
5 regional properties for C6A5A3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | ATP-dependent RNA helicase DEAD-box, conserved site | 278 - 286 | IPR000629 |
| domain | Helicase, C-terminal | 342 - 502 | IPR001650 |
| domain | DEAD/DEAH box helicase domain | 156 - 320 | IPR011545 |
| domain | Helicase superfamily 1/2, ATP-binding domain | 150 - 346 | IPR014001 |
| domain | RNA helicase, DEAD-box type, Q motif | 131 - 159 | IPR014014 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.282 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| tRNA methyltransferase activity | Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| wybutosine biosynthetic process | The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazopurine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFLYEKNFDL | QKKKALESLN | DALEKGLVDS | DIISLLNKIN | SLKNYFTTSS | CSGRISIMQM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PDLGDKLNAI | WLGKWHREVK | IEEVLDTINK | HDGGMLWFMV | HSPILHVSAK | TLEDAVELLN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LAMACGFKHS | NIKSVSHKKL | VVEIRSTERM | DIPLGSDGEL | WVNESYLVKI | VSMANLQLRR |
| 190 | |||||
| TKEKLRKLED | EIQKLKK |