C6A1V3

PR
Gene name
infB
Protein name
Probable translation initiation factor IF-2
Names
Species
Thermococcus sibiricus (strain DSM 12597 / MM 739)
KEGG Pathway
tsi:TSIB_0532
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

297-380 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C6A1V3

Entry ID Method Resolution Chain Position Source
AF-C6A1V3-F1 Predicted AlphaFoldDB

No variants for C6A1V3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C6A1V3

No associated diseases with C6A1V3

5 regional properties for C6A1V3

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 4 - 221 IPR000795
domain Translation elongation factor EFTu-like, domain 2 247 - 325 IPR004161
domain Small GTP-binding protein domain 8 - 157 IPR005225
domain Translation initiation factor IF- 2, domain 3 332 - 446 IPR023115
domain Elongation factor Tu-type domain 467 - 553 IPR029459

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKIRQPIIA VLGHVDHGKT SLLDRIRNTH VAEKEAGGIT QHIGATEVPI DVVKQLAGPL
70 80 90 100 110 120
LSLWKGEIKL PGLLFIDTPG HEAFTSLRAR GGSLADLAIL IIDVNEGFQP QTLESIEILR
130 140 150 160 170 180
KYKTPFVVAA NKIDRIKGWK VVENEPFLVN IKKQDQRAQQ DLETKLWELI GKFYELGFQV
190 200 210 220 230 240
NRFDRVKDFR KELAIIPISA KYGIGVPELL VLISGLAQKY LEEKLKIEVE GPARGTILEV
250 260 270 280 290 300
REEIGFGTTI DVIIYDGTLR KDDTIVVGGK DKAIVTKIRA LLKPKPLDEI RDPRYKFDHV
310 320 330 340 350 360
NEVSASAGIK IAAPDLEEAL AGSPVIAVRD EEELKRARRE ILEQIKSVII STDKVGVIVK
370 380 390 400 410 420
ADTIGSLEAL SKELHEKNIP IRKADVGNIS KTDVMEALSV KEEEPFYGVV IGFNVKVNED
430 440 450 460 470 480
AEEVAKAKNI PLFVNNIIYK LIEDYEAWIK AEEEKKKKEI LANTKFPGVI KLFPDERYVF
490 500 510 520 530 540
RRSHPAIVGI EVLEGRIKPG YPLIKQNGDK VGVIKSIKSK EDFLQEAKKG DQVAVAIEGA
550 560 570 580 590
IVGRHIHPGE ILYVDISKDD AIRLVKELRD MLDDTDIEAL KNTAKVKAQK DPFWGAL