C5JPM9

PR
Gene name
BDBG_05051
Protein name
Vacuolar membrane protease
Names
FXNA-related family protease 1
Species
Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis)
KEGG Pathway
bgh:BDBG_05051
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

547-646 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C5JPM9

Entry ID Method Resolution Chain Position Source
AF-C5JPM9-F1 Predicted AlphaFoldDB

No variants for C5JPM9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C5JPM9

No associated diseases with C5JPM9

1 regional properties for C5JPM9

Type Name Position InterPro Accession
domain Peptidase M28 165 - 340 IPR007484

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
metalloexopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATPRAQKFN PIAFTPGPVT LITTIVYLAL LIPILVISLV VPPAPETSPE GVNLTEAWRD
70 80 90 100 110 120
LQHLTGGFHP YNSRRNDDVH QWLLRRIDSI LRPTVEAGER PSANNDIPDV FVFDDNQSNL
130 140 150 160 170 180
TYSNGGVGKA AIVGVYFEGT NIIVYIRGTE DDPENWWERS NGKPKGKGGV LVNAHYDSVS
190 200 210 220 230 240
TGYGATDNGM GVVSLLQLLK YFTTPGNKPR KGLVLLFNNG EEDYLNGAHV FSQHPLSNFT
250 260 270 280 290 300
HTFLNLEGAG AGGRAALFRT TDTEVTRFYQ NAKHPFGSVL AADGFKMGLL RSQTDYVVFN
310 320 330 340 350 360
GILGLRGLDL AFIAPRSRYH TDQDDARHTS VDSLWHMLSA AIGTTEGLVS YTGTDFDGKS
370 380 390 400 410 420
QGLDKVNSGT GTLGVWFDMF GSAFAVFRLH TLFALSVTLL IVAPLVIFIT AIVLSKTDRM
430 440 450 460 470 480
YLFSMSKSLG GTDERVSLRG LRGLFRTPII LAVATVIPIG LAYLLEKVNP YIVHSSQFSV
490 500 510 520 530 540
WSMMISVWIF LAWFLACAAD FFRPSALHRA YSYTWIFIAT WVMLVINTVY ANQKGIAAGY
550 560 570 580 590 600
FVFFYFSGSF LATWVSYLEL FALPRKGDFA RQAIMHSGRP PSSLRSRLLT PSADELPSDT
610 620 630 640 650 660
GPHAEYPGDA DETDPTESTS LLRGQRTTFA NYRTGGTDGV VEGTDEGPSF KHEQSWSWTL
670 680 690 700 710 720
PRWTWVLQLL LLAPIVLILV GQLALFLTTS MSQVGSDGVS TFIVYLACAV FTTLLFAPLF
730 740 750 760 770 780
PFIHRFTYHI PTFLFLVFVG TLIYNLVAFP FSPANRLKMF FIQEVNLDDG SNTVSLSGIQ
790 800 810 820 830 840
PYLTDAINSI PSAAGQNITC DQSAFGKLEK CSWAGLPPRV LGQDHDRDTG IVSSDWMSYN
850 860 870 880 890 900
ITKTVGENKA RIEISGRNTR ACKLKFDKPV ADFQVSGSAV DHRMPHTSGQ GVAEIRLWSR
910 920 930 940 950 960
TWDRTWVVDI CWHDSHDKPE DDDGDDEKQD APRNGLSGKV ICLWSDSNQS DVIPALDELR
970 980
LYTPNWVAIS KSADGLVEAS HGITIQ