C5FRQ0

PR
Gene name
OPSB (MCYG_05372)
Protein name
Probable aspartic-type endopeptidase OPSB
Names
Species
Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

28-142 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C5FRQ0

Entry ID Method Resolution Chain Position Source
AF-C5FRQ0-F1 Predicted AlphaFoldDB

No variants for C5FRQ0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C5FRQ0

No associated diseases with C5FRQ0

2 regional properties for C5FRQ0

Type Name Position InterPro Accession
domain Peptidase family A1 domain 58 - 394 IPR033121
domain Secreted aspartic endopeptidase 69 - 395 IPR033876

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Lipid-anchor, GPI-anchor
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
anchored component of membrane The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
aspartic-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRGDSFIWSL TTAASLLYAT VESLQVVKRD NPSIVGFDIE RFQVAKPVHR DIIAKRASGK
70 80 90 100 110 120
TVSQDLDNQT IRAHIDTGSS DLWVNTDDSQ FCSSRRSPCR EGGTFDSSSS STYQLVSNDF
130 140 150 160 170 180
NISYVDGSGA SGDYVTDVIE VGGIQLKEFQ FAIGHTSSSP LGVLGIGYEA GEALVSRFGD
190 200 210 220 230 240
ESYPNLPAAL VKAGHIRSNA YSLWLNDLSA SRGQILFGGV DTGKFEGKLQ TVPVLHTSGG
250 260 270 280 290 300
DYTSLVIALT SVGIRTASEG SLDTFPAQPV AVAMDSGSSL SYLPDALAAK IYNSIDAVFD
310 320 330 340 350 360
PSNNLAFVPC SMVNDDRKLV FTFSSPQITV GMDELVIDLG PDANGNEATF RDGSKACVFG
370 380 390 400 410 420
IAPAGRSISI LGDTVLRSAY LVYDLDNNEI SIAPTRFNST VTNIMEIGTG KNSVPDATGV
430 440 450 460 470
PNAVTSAPIT QATGLSGIET GVPGARPTSR GAAPTMRPDV TFGVAAAGLA GAGILFAFM