Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for C5DZR8

Entry ID Method Resolution Chain Position Source
AF-C5DZR8-F1 Predicted AlphaFoldDB

No variants for C5DZR8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C5DZR8

No associated diseases with C5DZR8

1 regional properties for C5DZR8

Type Name Position InterPro Accession
domain Methyltransferase domain 71 - 216 IPR025714

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion outer membrane ; Single-pass membrane protein
  • Vacuole membrane ; Single-pass membrane protein
  • Preautophagosomal structure membrane ; Single-pass membrane protein
  • Is recruited to the preautophagosomal structure during mitophagy and imported into the vacuole along with mitochondria during starvation
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
phagophore assembly site membrane A cellular membrane associated with the phagophore assembly site.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
autophagy The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTSTEGTGGG DGKGISGFSD IERRSILDPH LSVLELLRRP SDTRPHEALK GEVSDIVGNC
70 80 90 100 110 120
AGTTGTGNGS ISQSWQTIHR NDSCLSVVPE RCPSQATAAG ILSSSDTSED EPDAVNSPSA
130 140 150 160 170 180
VHQQLHATPP QKHTKSLEDY RSLNVGIPLV LPEDSNNINN NNKNGSTTGS NGEEDDNDTI
190 200 210 220 230 240
TKSLNSSSNS FIMPKLSLSQ KTQKFRILVL GRPGLKFYHS IPKKYQHMFE LPRSHDPAEF
250 260 270 280 290 300
KQYTGILVVF QELKEMVSLL NRVCQCNPNR PVIPVCQSGQ RQQVRNLLES LLKNRLVSLL
310 320 330 340 350 360
YPPVVVNNQP DLLGMFRFLQ ELSKTVSDNS DMDAEEPNNG SKRLKRSLQR KKKKFIETSA
370 380 390 400 410 420
ERNGRPHKKR HNNEKVNRWV LWGVSLTLGV GVGYCISHLV SSTWISLTTN PLGPVDPESV
430 440 450 460 470 480
SKDLFVFDRQ ELKLGEMDMD SDHPFGHALF LFKQALKQWN LAVKQFLGRH LSCMERIGPA
490 500
NCLEWPTSDE HTNRVLALGY VML