C5DEL5

PR
Gene name
SEY1
Protein name
Protein SEY1
Names
Species
Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)
KEGG Pathway
lth:KLTH0C10230g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

358-432 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C5DEL5

Entry ID Method Resolution Chain Position Source
AF-C5DEL5-F1 Predicted AlphaFoldDB

No variants for C5DEL5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C5DEL5

No associated diseases with C5DEL5

2 regional properties for C5DEL5

Type Name Position InterPro Accession
domain GB1/RHD3-type guanine nucleotide-binding (G) domain 35 - 265 IPR030386
domain Sey1/RHD3-like, three-helix bundle domain 329 - 738 IPR046758

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
  • Enriched in the cortical ER
  • Concentrated in punctae along the ER tubules
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

1 GO annotations of biological process

Name Definition
endoplasmic reticulum organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGETEEAIQL INEEKEFNSS TLQYFQKCVK ERDVGVDYHV ISVFGSQSSG KSTLLNALFH
70 80 90 100 110 120
TQFDTMNAKV KRQQTTKGIW LGHTTRIATL ENSLTPVKDL FVLDVEGSDG AERGEDQDFE
130 140 150 160 170 180
RKAALFAIAI SEVLIVNMWE QQVGLYQGNN MALLKTVFEV NLSLFGHQND HKVLLLFVIR
190 200 210 220 230 240
DHVGVTPLSS LQETLEAELN AIWSDLAKPE GCENSSLYDF FDLKFTALAH KVLQPDLFME
250 260 270 280 290 300
NVKELGNKFS SETPGKSFFK PEYHHNLPLD GWTMYAGNCW NQIETNKDLD LPTQQILVAK
310 320 330 340 350 360
FKTEEISNQA LALLLENYPV DLHCRELSDL AGKLQELKSL CLQEYDTYAS RYAKPVYMDN
370 380 390 400 410 420
RRDLSHKIEN KFKETISKFL DVQKEDLLSQ VEKDLTERSR STPFVTKMKE ARKKAFDAFE
430 440 450 460 470 480
ELLLQFTKLE LVASLSDENE AFSIALDEAC SNQSRKQLKQ SVNRISKSVS SGIKEDIFFL
490 500 510 520 530 540
LAHPELDLWD KVMEKFNEIV SDSTERYAVD DEKFDFQVGL SEEENQKVYK KVRSNAWTNL
550 560 570 580 590 600
YEFVHGYLNE DNVVSILRDR FENKFRYDEH DSPRLWRNEE EIDNAFRVAK EHALEVLNVL
610 620 630 640 650 660
SLASNSDHVE IVPDVPLSSG LDDEELEGEY EDEEGIYHEK GFAHILTASQ RERAVQKFKR
670 680 690 700 710 720
QANTTVIEAK RSIIRTTTHI PLYVYALLVV LGWNEFMIVI RNPLFVTLLV ILSVTAYFVH
730 740 750 760 770 780
KLNLWAPILA LVNSAVSETK ALARNKLKVI LDDDSSSSSK ASKEPTEEYE MQDLAKSSTT
GTG