C5D324

PR
Gene name
recU
Protein name
Holliday junction resolvase RecU
Names
Recombination protein U homolog
Species
Geobacillus sp (strain WCH70)
KEGG Pathway
gwc:GWCH70_2106
EC number
3.1.21.10: Endodeoxyribonucleases producing 5'-phosphomonoesters
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-57 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C5D324

Entry ID Method Resolution Chain Position Source
AF-C5D324-F1 Predicted AlphaFoldDB

No variants for C5D324

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C5D324

No associated diseases with C5D324

No regional properties for C5D324

Type Name Position InterPro Accession
No domain, repeats, and functional sites for C5D324

Functions

Description
EC Number 3.1.21.10 Endodeoxyribonucleases producing 5'-phosphomonoesters
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
crossover junction endodeoxyribonuclease activity Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).
magnesium ion binding Binding to a magnesium (Mg) ion.
nucleic acid binding Binding to a nucleic acid.

3 GO annotations of biological process

Name Definition
chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIFKYPGGKT YETKQMNKSI RPFQPNYGNR GMTLEEDLNA TNEYYREHGI AVIHKKPTPV
70 80 90 100 110 120
QIVRVDYPKR SAAVIKEAYF KQASTTDYNG VYRGKYIDFE AKETKNKTSF PLKNFHEHQI
130 140 150 160 170 180
HHMQQVLRHG GICFVILRFT TLNEVYLLDA NHLIMFWEQQ RSGGRKSIPK REIERYGHYI
190 200
ALGYQPRIDY ISVVEKVYFS H