C5CT24

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Variovorax paradoxus (strain S110)
KEGG Pathway
vap:Vapar_3514
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

671-772 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C5CT24

Entry ID Method Resolution Chain Position Source
AF-C5CT24-F1 Predicted AlphaFoldDB

No variants for C5CT24

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C5CT24

No associated diseases with C5CT24

9 regional properties for C5CT24

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 18 - 146 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 326 - 458 IPR001247-2
domain S1 domain 621 - 692 IPR003029
domain K Homology domain 554 - 619 IPR004087
domain K Homology domain, type 1 558 - 616 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 149 - 212 IPR015847-1
domain Exoribonuclease, phosphorolytic domain 2 463 - 531 IPR015847-2
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 245 - 322 IPR015848
domain RNA-binding domain, S1 622 - 692 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSLFNKVTKS FQWGDKTVVM ETGEIARQAS GAVVVDIDGT VILATVVASK TAKPGQDFFP
70 80 90 100 110 120
LTVDYIEKTY AAGKIPGSFF KREAKPSEHE TLTSRLIDRP IRPLFPEGFL NEVHVVIHTL
130 140 150 160 170 180
SLNPEVDADI AAMIGVSAAL SISGIPFSGP IGAARVGYIN GQYVLNPGQT ARKDSQMDLV
190 200 210 220 230 240
VAGTEAAVLM VESEAQQLSE EIMLGGVVFG HEQANIAINA IHELVRDAGK PVWDWQAPAE
250 260 270 280 290 300
DEAFVAKVKS LAEEKLRAVY QIRSKQARTQ ALREANASVM NTLKESGEPF DAGKVNDLLF
310 320 330 340 350 360
AIESKIVRSQ ILSGEPRIDG RDTRTVRPIE IRNSVLPRTH GSALFTRGET QGLVVTTLGT
370 380 390 400 410 420
ERDAQRIDAL AGEYEDRFLF HYNMPPFATG EVGRMGSTKR REIGHGRLAK RALVAVLPTK
430 440 450 460 470 480
EEFPYTIRVV SEITESNGSS SMASVCGGCL SMMDAGVPMK AHVAGIAMGL IKEDNRFAVL
490 500 510 520 530 540
TDILGDEDHL GDMDFKVAGT TNGITALQMD IKIQGITKEI MQVALAQAKE ARMHILGKMQ
550 560 570 580 590 600
EAMGEAKTEV SQFAPRLTTL KINPEKIRDV IGKGGAVIRG LQEETGTTIN IDEDGTITIA
610 620 630 640 650 660
STDPEKAEFA KKRIEQITAE VEIGKVYEGP VTKILDFGAL INLLPGKDGL LHISQIAHER
670 680 690 700 710 720
VEKVTDYLSE GQIVKVKVLE TDEKGRVKLS MKALTERPAG MEYSERPPRE DRGDRGDRGG
730 740 750 760 770
ERRERSDRGD RGGDRGERAP RFNSEQQQQP RSNEQQPAPV GEQPYAPRDS QE