C5CH91

PR
Gene name
dnaA
Protein name
Chromosomal replication initiator protein DnaA
Names
Species
Kosmotoga olearia (strain ATCC BAA-1733 / DSM 21960 / TBF 1951)
KEGG Pathway
kol:Kole_0001
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

46-132 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C5CH91

Entry ID Method Resolution Chain Position Source
AF-C5CH91-F1 Predicted AlphaFoldDB

No variants for C5CH91

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C5CH91

No associated diseases with C5CH91

4 regional properties for C5CH91

Type Name Position InterPro Accession
domain AAA+ ATPase domain 135 - 268 IPR003593
domain Chromosomal replication initiator, DnaA C-terminal 350 - 438 IPR013159
domain Chromosomal replication initiator protein DnaA 104 - 320 IPR013317
domain DnaA N-terminal domain 4 - 61 IPR024633

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA replication origin binding Binding to a DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.

2 GO annotations of biological process

Name Definition
DNA replication initiation The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate.
regulation of DNA replication Any process that modulates the frequency, rate or extent of DNA replication.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSNRIISILK KRLARKTWDN WFTTFQVKKV TDDKIIFSVG NLFIKDWLQS KYGSVISKAI
70 80 90 100 110 120
KEAYGKNLDY EIVYETTEPE AFNKSNESYK GPLVKKKPLL ISNLNANYTF ENFVVGPENR
130 140 150 160 170 180
VLYEVSLEIS RNPGRYNPFF VYGMVGLGKT HLLQAIAHKI MELHPEMRVL YITSEQFMND
190 200 210 220 230 240
MIDSIKYGSV RDFREHYRKK ADVLLIDDIQ FLIGKNGVQK ELFHTFNELY DAGKQIVICS
250 260 270 280 290 300
DRNPEELNGF HDRLVSRFQM GMVMEICPPE KDTRFKIAKK FAERESVSLP DDVAQLLADS
310 320 330 340 350 360
VDGNLRILRG VIIKLIVQSS INKERIGAAL TNQILAAFNK TTVSIKRMKE EDLIMSTIEA
370 380 390 400 410 420
VMGVSPEEIK GTSRKQNIVL SRQLLMYILK RHHGKSIKEI SKITGKRHST VIHSIKKIEM
430 440
SVIKGNTVVK EKLAKILNTM ATSSAAG